Results 351 to 360 of about 2,974,203 (387)
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Apoptosis, 1999
In addition to its role as a mediator of innate pro-inflammatory responses following bacterial lipopolysaccharide (LPS) binding, the 55kDa glycosyl-phosphatidylinositol-linked macrophage plasma membrane glycoprotein CD14 is now also known to play a role in phagocytic clearance of apoptotic cells.
Andrew Devitt, Christopher D. Gregory
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In addition to its role as a mediator of innate pro-inflammatory responses following bacterial lipopolysaccharide (LPS) binding, the 55kDa glycosyl-phosphatidylinositol-linked macrophage plasma membrane glycoprotein CD14 is now also known to play a role in phagocytic clearance of apoptotic cells.
Andrew Devitt, Christopher D. Gregory
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Apoptosis and aging: breast cells and apoptosis
Maturitas, 2001The major events involved in tissue homeostasis are proliferation, differentiation and apoptosis. Senescence is a non-dividing state of the cell, usually associated with terminal differentiation, and preceding cell death. The three pathways result in suppression of cell proliferation. Apoptosis during aging can contribute to the elimination of damaged,
Patricia Forgez +4 more
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Cytokine & Growth Factor Reviews, 2002
Apoptosis in mammalian cells can be initiated through two major interrelated pathways, one involving engagement of the TNF family of death receptors, the other involving the release of cytochrome c from mitochondria. Unlike other members of the TNF ligand family, TNF-related apoptosis-inducing ligand (TRAIL) preferentially induces apoptosis in tumor ...
Baetu, Tudor, Hiscott, John
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Apoptosis in mammalian cells can be initiated through two major interrelated pathways, one involving engagement of the TNF family of death receptors, the other involving the release of cytochrome c from mitochondria. Unlike other members of the TNF ligand family, TNF-related apoptosis-inducing ligand (TRAIL) preferentially induces apoptosis in tumor ...
Baetu, Tudor, Hiscott, John
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Apoptosis in Alzheimer’s disease: insight into the signaling pathways and therapeutic avenues
Apoptosis, 2023Sneha Kumari, Rishika Dhapola, D. Reddy
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1997
Publisher Summary The genetic analysis of apoptosis, or programmed cell death, provides important information on the biology of naturally occurring cell death. Identification of genes regulating apoptosis has confirmed that this process follows a similar paradigm in all multicellular organisms.
Desnoyers, S, Hengartner, M O
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Publisher Summary The genetic analysis of apoptosis, or programmed cell death, provides important information on the biology of naturally occurring cell death. Identification of genes regulating apoptosis has confirmed that this process follows a similar paradigm in all multicellular organisms.
Desnoyers, S, Hengartner, M O
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Biochemistry and Cell Biology, 2000
Here we review the different apoptotic DNases. From a functional point of view, DNases implicated in apoptosis may be classified into three groups: the Ca2+/Mg2+ endonucleases, the Mg2+-endonucleases, and the cation-independent endonucleases. The first group includes DNase I which has no specificity for the linker region, DNase gamma which has some ...
Alicia Torriglia, M.F. Counis
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Here we review the different apoptotic DNases. From a functional point of view, DNases implicated in apoptosis may be classified into three groups: the Ca2+/Mg2+ endonucleases, the Mg2+-endonucleases, and the cation-independent endonucleases. The first group includes DNase I which has no specificity for the linker region, DNase gamma which has some ...
Alicia Torriglia, M.F. Counis
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Apoptosis, 2001
Infection with the human immunodeficiency virus type 1 (HIV-1) leads to progressive immunodeficiency and onset of opportunistic infections and neoplasms. The loss of immune competence is associated with declines in both the functionality and the number of CD4+ lymphocytes.
Yonghong Zhu +2 more
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Infection with the human immunodeficiency virus type 1 (HIV-1) leads to progressive immunodeficiency and onset of opportunistic infections and neoplasms. The loss of immune competence is associated with declines in both the functionality and the number of CD4+ lymphocytes.
Yonghong Zhu +2 more
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Apoptosis and Clearance of Apoptotic Cells.
Annual Review of Immunology, 2018The human body generates 10-100 billion cells every day, and the same number of cells die to maintain homeostasis in our body. Cells infected by bacteria or viruses also die.
S. Nagata
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Mammalian caspases: structure, activation, substrates, and functions during apoptosis.
Annual Review of Biochemistry, 1999Apoptosis is a genetically programmed, morphologically distinct form of cell death that can be triggered by a variety of physiological and pathological stimuli. Studies performed over the past 10 years have demonstrated that proteases play critical roles
W. Earnshaw, L. M. Martins, S. Kaufmann
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The American Journal of Medicine, 2000
During normal bone remodeling, the rate of supply of new osteoblasts and osteoclasts and the timing of the death of osteoclasts, osteoblasts, and osteocytes by apoptosis are critical determinants of the initiation of new BMUs and the extension or reduction of the lifetime of existing ones.
Stavros C. Manolagas +1 more
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During normal bone remodeling, the rate of supply of new osteoblasts and osteoclasts and the timing of the death of osteoclasts, osteoblasts, and osteocytes by apoptosis are critical determinants of the initiation of new BMUs and the extension or reduction of the lifetime of existing ones.
Stavros C. Manolagas +1 more
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