Survey among adult users of semaglutide for weight loss in Denmark: User characteristics, treatment expectations and experienced effects. [PDF]
Abstract Aims Since the launch of semaglutide for weight loss (Wegovy®, SEMA‐WL) in late 2022, there has been a huge increase in new users of SEMA‐WL. We explored characteristics, treatment expectations and experienced effectiveness and side effects among Danish adults using SEMA‐WL. Materials and Methods A questionnaire‐based survey was conducted from
Sørensen MS +4 more
europepmc +2 more sources
Effect of Intradermal Morphine on Histaminergic and Non-Histaminergic Itch: A Randomised, Single-Blinded, Human Study. [PDF]
ABSTRACT Itch can be a side‐effect of drugs like opioids, with prevalence depending on the route of administration. This study aimed to investigate if morphine (1) induced itch and neurogenic inflammation after intradermal injection and (2) modulates the responses to locally experimentally induced histaminergic and non‐histaminergic itch.
Lo Vecchio S +6 more
europepmc +2 more sources
Preimmunization of SPF Mice With Capsid Virus-like Particle Has no Effect on CD8<sup>+</sup> Immune Memory and Skin Inflammation in an Ovalbumin-Induced Dermatitis Model. [PDF]
ABSTRACT Specific pathogen‐free (SPF) laboratory mice have in recent years been criticized for their limited bench to bedside translational value, specifically within immunological and inflammatory research, due to their immature immune system caused by restricted pathogen exposure.
Kern KS +7 more
europepmc +2 more sources
The Inflammatory Response in the Murine Ovalbumin-Induced Skin Inflammation Model Is Robust Despite Major Gut Microbiota Differences. [PDF]
ABSTRACT Valid pre‐clinical animal models are essential for effective drug development in inflammatory skin diseases like atopic dermatitis. Most murine models exhibit low‐to‐moderate inflammatory responses with significant variability, undermining their validity and contributing to high drug attrition rates.
Henriksen IW +5 more
europepmc +2 more sources
Psyches Iatreion – sjelens apotek
exaly +2 more sources
This study investigates how diets that exert effects on the gut microbiome: i) an inulin‐fortified and ii) a calcium‐deficient diet, affect the hepatic transcriptome and metabolome of ovariectomized rats. Inulin ingestion affects hepatic gene expression and is associated with an upregulation of ferritin synthesis‐related genes and liver ferritin ...
Xiaorui Zhao +6 more
wiley +1 more source
Intramuscular vasopressin: A feasible intervention for prehospital hemodynamic stabilization in porcine hemorrhagic shock and whole blood transfusion. [PDF]
Abstract Background Hemorrhagic shock is the leading cause of preventable prehospital trauma deaths. While arginine vasopressin (AVP) is a well‐known hormone with vasopressor effects, its potential for hemodynamic stabilization in prehospital hemorrhagic shock remains underexplored.
Renberg M +5 more
europepmc +2 more sources
Abstract Aims To investigate the effects of empagliflozin on measured glomerular filtration rate (mGFR), estimated plasma volume (PV) and estimated extracellular volume (ECV) in a cohort of patients with type 2 diabetes (T2D) and high risk of cardiovascular events.
Mikkel Jürgens +12 more
wiley +1 more source
Penerapan Standar Pelayanan Kefarmasian Di Apotek Kota Magelang
Penelitian ini bertujuan untuk mengetahui gambaran penerapan standar pelayanan kefarmasian di Apotek Kota Magelang. Penelitian ini adalah penelitian deskriptif. Sampel dalam penelitian ini adalah apotek di Kota Magelang.
Elmiawati Latifah +2 more
doaj +1 more source
As it is unclear whether quetiapine increases the risk of fatal methadone poisoning, the combined effects of three accumulated doses of methadone, and quetiapine was investigated in conscious freely moving rats using telemetry and compared to vehicle and treatment with each drug alone.
Freja Drost Andersen +7 more
wiley +1 more source

