Results 101 to 110 of about 336,297 (296)

Transplantation of GABAergic Interneuron Progenitors Restores Cortical Circuit Function in an Alzheimer's Disease Mouse Model

open access: yesAdvanced Science, EarlyView.
Transplantation of medial ganglionic eminence (MGE) interneuron progenitors into APP/PS1 cortices restored the slow oscillation characteristic of Alzheimer's disease. Donor cells survived, migrated, and matured into functional GABAergic interneurons, forming synaptic connections.
Shinya Yokomizo   +16 more
wiley   +1 more source

Long-term exercise training inhibits inflammation by suppressing hippocampal NLRP3 in APP/PS1 mice

open access: diamond, 2023
Xue Li   +5 more
openalex   +1 more source

Mammalian Proteome Profiling Reveals Readers and Antireaders of Strand‐Symmetric and ‐Asymmetric 5‐Hydroxymethylcytosine‐Modifications in DNA

open access: yesAdvanced Science, EarlyView.
We investigate by proteomics studies how strand‐symmetric and ‐asymmetric cytosine 5‐modifications in DNA are selectively recognized by the nuclear proteome. Using promoter probes with defined modification patterns, we identify tissue‐specific reader proteinsincluding MYC, MAX, and RFX5that discriminate 5‐hydroxymethylcytosine symmetry and sequence ...
Lena Engelhard   +8 more
wiley   +1 more source

Evaluation of Mobile Apps Effectiveness in Children with Autism Social Training via Digital Social Stories

open access: gold, 2020
Agathi Stathopoulou   +5 more
openalex   +2 more sources

Rapid Decentralized Prostate Cancer Risk Stratification by Portable Liquid Biopsy Analysis within a Clinical Biosensor Validation Framework

open access: yesAdvanced Science, EarlyView.
In this work, we showcased two significant scientific advances in (i) developing a portable biosensor technology for rapid decentralized prostate cancer urinary biomarker testing and reporting, with superior performance to current clinical testing practice; and (ii) proposing a clinical validation framework (for our biosensor development) which can be ...
Kevin M. Koo   +14 more
wiley   +1 more source

Local subdifferentials and multivariational inequalities in Banach and Frechet spaces [PDF]

open access: yesOpuscula Mathematica, 2008
Some functional-topological concepts of subdifferential and locally subdifferential maps in Frechet spaces are established. Multivariational inequalities with an operator of the pseudo-monotone type, connected with subdifferential maps, are considered.
Pavlo O. Kasyanov   +2 more
doaj  

Mobile app for prolonged grief among bereaved parents: study protocol for a randomised controlled trial [PDF]

open access: gold, 2021
Rakel Eklund   +4 more
openalex   +1 more source

Proteogenomic Characterization Reveals Subtype‐Specific Therapeutic Potential for HER2‐Low Breast Cancer

open access: yesAdvanced Science, EarlyView.
Multiomic profiling of HER2‐low breast cancer identifies three proteomic subtypes with distinct therapeutic strategies: endocrine, antiangiogenic, and anti‐HER2 therapies. Genomic and lactate modification landscapes are detailed, providing insights for precise management.
Shouping Xu   +20 more
wiley   +1 more source

ENERGY AND CLIMATE CHANGE. NUCLEAR, PROS AND CONS [PDF]

open access: yesAnnals of the University of Oradea: Economic Science, 2014
It’s needless to say that nuclear is a hot subject. It arouses public imagination, suspicion, and fear. It has always animated scientists’ minds and souls and after they discovered how to manipulate the atom, the public conscience has become aware of its
BENEA Ciprian-Beniamin
doaj  

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