Results 171 to 180 of about 521,681 (299)

Depictions of Depression in Generative AI Video Models: Mixed Methods Study of OpenAI's Sora 2. [PDF]

J Med Internet Res
Flathers M, Smith G, Herpertz J, Zhou Z, Torous J.   +4 more
europepmc   +1 more source

Early Spatial and Contextual Coding Deficits in Hippocampal CA1 Precede Performance Decline in an Alzheimer's Disease Model

Advanced Science, EarlyView.
Two‐photon calcium imaging in behaving 5xFAD mice reveals early CA1 coding deficits before behavioral decline. Task‐related place cell activity and splitter cell trajectory coding are impaired, with reduced retrospective dominance and greater prospective weighting.
Yimei Li, Mary Ann Go, Hualong Zhang, Robertas Aleksynas, Juliana Kim, Mingyang Gao, Seigfred Prado, Magdalena Sastre, Simon R. Schultz   +8 more
wiley   +1 more source

Multi-Omics Analysis Reveals That Aβ42- Me3 Co-Aggregation Induces Mitophagy Blockade in Early Stages of Alzheimer's Disease. [PDF]

MedComm (2020)
Zhu W, Zhang Y, Li P, Zhong Y, Lin Y, Liu X.   +5 more
europepmc   +1 more source

Tau Aggregate Imaging and Transcriptomics of Alzheimer's Disease Brain at Different Stages of Disease

Advanced Science, EarlyView.
The protein aggregates and gene expression in the middle temporal gyrus (MTG) and somatosensory cortex (SOM) of the postmortem brains of 13 Alzheimer's disease patients were studied in detail, revealing that small hyperphosphorylated tau aggregates increase with Braak stage driven by microglial inflammation.
Elizabeth A. English, Dorothea Böken, Matthew W. Cotton, Matthew R. Cheetham, Johanna S. Jackson, Georg Meisl, John S. H. Danial, Paul M. Matthews, Nurun N. Fancy, David Klenerman   +9 more
wiley   +1 more source

The Effect of Business Mentoring, Digital Capability, and Quality Management Capacity on MSMEs’ Export Performance: The Mediating Role of Export Readiness

Journal the Winners
This study examines the effects of business mentoring, digital capability, and quality management capacity on MSMEs’ export performance, with export readiness serving as a mediating variable. The study was conducted among MSMEs in DKI Jakarta.
Intan Maria Lewiayu Vierke, Muhammad Aqib Shafiq   +1 more
doaj  

Play to move: A mixed-methods prospective observational study of exergaming versus traditional exercise interventions in children with Down syndrome. [PDF]

J Int Med Res
Baron E, Ulaganathan N, Kurniawan S.
europepmc   +1 more source

Interfacial Salinity–Transport Matching in 3D Solar Evaporators: A Framework for Brine‐Stable Solar Interfacial Evaporation

Advanced Science, EarlyView.
A transport‐matching framework is developed to evaluate brine‐stable 3D solar evaporators beyond evaporation rate alone. Using PVA/GNP porous evaporators as a model system, the study shows that stable brine evaporation requires balanced heat generation, liquid replenishment, salt redistribution, and vapor removal rather than maximum dry temperature or ...
Mohammad Sajad Sorayani Bafqi, Arun Prakash Aranga Raju, Omid Doustdar, Reza Nekouie Esfahani, Ali Sadaghiani   +4 more
wiley   +1 more source

A Nudge Theory-Based Mobile Health Intervention for Self-Management in Young and Middle-Aged Patients With Hypertension: Mixed Methods Pilot Study. [PDF]

JMIR Form Res
Yang Y, Xu W, Zhang Y, Yang X, Li L, Yang J.   +5 more
europepmc   +1 more source

MXene‐Based Room‐Temperature NO2 Gas Sensors: A Meta‐Analysis

Advanced Science, EarlyView.
This study presents the first comprehensive meta‐analysis of MXene‐based NO2 sensors, decoding 32 study characteristics across 61 peer‐reviewed studies. By isolating materials chemistry as the primary performance driver over device‐level parameters, the authors establish a methodological blueprint and a predictive structure–function map to accelerate ...
Alexander Khort, Jerome Geyer‐Klingeberg, Andreas Rathgeber, Suelen Barg   +3 more
wiley   +1 more source

Near‐Infrared Fluorescent PROTAC Enables Theranostic Imaging and Selective Tau Degradation in Alzheimer's Disease

Advanced Science, EarlyView.
Here, we report a novel NIR fluorescent PROTAC platform that enables real‐time imaging and targeted degradation of Alzheimer's p‐Tau. Our lead compound effectively clears p‐Tau, reduces APP/Aβ, and alleviates cognitive deficits in AD mice. This work demonstrates a theranostic strategy for visualizing degradation and developing next‐generation AD ...
Ziwei Ren, Qian Yue, Ning Gao, Qiu‐Lian Hao, Yan Huo, Chuchu Li, Xinyue Leng, Lu‐Lu Sun, Maggie Pui Man Hoi, Hai‐Hao Han, Mingliang Ma, Xu‐Wen Li   +11 more
wiley   +1 more source