Results 211 to 220 of about 336,297 (296)

Hub genes and diagnostic model associated with mitochondrial function in Alzheimer's disease

Animal Models and Experimental Medicine, EarlyView.
Alzheimer's disease (AD) is the most common neurodegenerative disorder, and mitochondrial dysfunction has been confirmed in AD patients and mouse models. However, the pathogenic genes associated with AD and early diagnostic methods based on mitochondrial function remain to be explored.
Xuchao Zhu, Ling Zhang, Chuan Qin
wiley   +1 more source

Clinical validation of a frailty management mHealth tool in a cohort of community-dwelling older adults: the Geras Fit-Frailty App. [PDF]

BMJ Open
Kennedy CC, Ioannidis G, Rockwood K, Relan A, Adachi J, Papaioannou A, Fit-Frailty App Working Group.   +6 more
europepmc   +1 more source

Polyphenol diet and exercise as neuroprotective factors in a Drosophila model of Alzheimer's disease

Animal Models and Experimental Medicine, EarlyView.
Moderate exercise and low‐dose ellagic acid supplementation improved motor performance, learning, and longevity in a transgenic Drosophila model of Alzheimer's disease. Both interventions showed hormetic effects—that is, beneficial at low levels, but detrimental at higher intensities or doses.
Michelle Morgan, Zaida Lopez Rodriguez, Richard E. Hartman   +2 more
wiley   +1 more source

Supporting Dementia Caregiving With a Mobile Care Ecosystem: Development and Mixed Methods Study. [PDF]

JMIR Aging
Malhotra C, Yue Y, Ramakrishnan C, Shah S, Chen W, Yap P, Cheong CY, Teo I, Wee SL, Lan X, Chen Y, Chong CS, Huang X, Chua I.   +13 more
europepmc   +1 more source

Implementing Computer Vision in Android Apps and Presenting the Background Technology with Mathematical Demonstrations [PDF]

Roland Szabó
openalex   +1 more source

Establishment of a mouse model of TMAO‐induced cardiac injury and application of MICT intervention

Animal Models and Experimental Medicine, EarlyView.
This study aims to explore the establishment of an animal model of cardiac injury induced by trimethylamine‐N‐oxide (TMAO), a metabolite secreted by gut microorganisms, and to investigate its application in moderate‐intensity continuous training (MICT) intervention.
Zhongping Xie, Hong Zou, Lijing Gong, Minghui Lin, Caihua Huang   +4 more
wiley   +1 more source

The complexity of dementia development and its comorbidities: The collaborative cross‐mouse population for multivarious tasks approach

Animal Models and Experimental Medicine, EarlyView.
The increasing prevalence of dementia and related neurodegenerative diseases—including Alzheimer's disease, Parkinson's disease, multiple sclerosis, and amyotrophic lateral sclerosis—poses a growing public health challenge. These conditions have traditionally been studied as isolated central nervous system disorders, but emerging evidence points to ...
Osayd Zohud, Iqbal M. Lone, Kareem Midlej, Fuad A. Iraqi   +3 more
wiley   +1 more source

Feasibility of the breastfeeding peer support application-perspectives of peer supporters and breastfeeding mothers. [PDF]

Int Breastfeed J
Ikonen R, Niela-Vilen H.
europepmc   +1 more source

FELASA Congress 2025

Animal Models and Experimental Medicine, EarlyView.
Themed “Reducing Severity in Animal Research,” FELASA 2025 Congress attracted experts and scholars from the global laboratory animal sciences field. Abstract The FELASA 2025 Congress, themed “Reducing Severity in Animal Research,” convened global experts in laboratory animal sciences to discuss ethical advancements, welfare standards, and innovative ...
Lai Wei
wiley   +1 more source

Building Molecules by a Self‐Replicator That Catalyzes Acyl Hydrazone Formation

Angewandte Chemie, EarlyView.
A self‐replicator efficiently catalyzes the formation of acyl hydrazone bonds between a set of different substrates. In addition to previously reported (bond‐breaking) catalytic activity, this renders the self‐replicator highly promiscuous, which is a good starting point for Darwinian experiments en route to de‐novo life.
Kayleigh S. van Esterik, Tommaso Marchetti, Sijbren Otto   +2 more
wiley   +2 more sources