Results 111 to 120 of about 1,002,978 (303)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

How the Housing and Financial Wealth Effects have changed over Time [PDF]

open access: yes
We measure the “evolution” of the housing and financial wealth effects over time by estimating the dynamic responses of consumption to both forms of wealth in the United States over different time periods from 1952 to 2009.
Derek Stimel, Ryan R. Brady
core  

Present  Status  and  Development  Trend  of  Stainless  Steel  in  China

open access: yesTeshugang, 2007
The  amount  of  annual  apparent  consumption  of  stainless  steel  in  China  in  2005  was  up  to5220000  t,  being  6  times  the  amount  of  annual  apparent  consumption  in  1998,at  the  some  time  the  amount  of  annual  output  of ...
程鹏辉, 贺东风, 田乃媛
doaj  

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Forecasting Seasonal UK Consumption Components [PDF]

open access: yes
Periodic models for seasonal data allow the parameters of the model to vary across the different seasons. This paper uses the components of UK consumption to see whether the periodic autoregressive (PAR) model yields more accurate forecasts than non ...
Clements, M.P., Smith, J.
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Energy Use By Apartment Tenants When Landlords Pay For Utilities [PDF]

open access: yes
Energy costs are included in the monthly rent of one fourth of U.S. apartment residents. Because these tenants do not face the marginal cost of their own energy use, they have little incentive to use energy efficiently.
Arik Levinson
core  

Re-Visting the Electricity-Growth Nexus in South Africa

open access: yesStudies in Business and Economics, 2016
This research study contributes to the ever-expanding literature by examining multivariate cointegration and causality relationships between electricity consumption, economic growth and other growth determinants for quarterly South African data collected
Phiri Andrew, Nyoni Bothwell
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Fine‐scale measurement of diffusivity in a microbial mat with nuclear magnetic resonance imaging

open access: yes, 2001
Noninvasive 1H‐nuclear magnetic resonance (NMR) imaging was used to investigate the diffusive properties of microbial mats in two dimensions. Pulsed field gradient NMR was used to acquire images of the H2O diffusion coefficient, Ds, and multiecho imaging
Damgaard, L.   +5 more
core  

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