Results 161 to 170 of about 605,121 (246)

Characterization of peripapillary vascular density in traumatic optic neuropathy. [PDF]

Am J Ophthalmol Case Rep
Snyder BM, Larsson J, Vu AF, Liu YA, Homer NA.   +4 more
europepmc   +1 more source

Blending technique to enhance apparent density

Metal Powder Report, 1993
openaire   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Visual perception of longitudinal waves: theory and observations. [PDF]

Sci Rep
Tyler CW, Solomon JA, Anstis SM.
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Optimisation of the WC-Co Composite Manufacturing Process Using Spark Plasma Sintering Technology with the DOE Methodology. [PDF]

Materials (Basel)
Kruzel R, Dembiczak T, Bałaga Z, Lis M, Kołacz D, Wachowicz J, Kuśmierczak S, Náprstková N.   +7 more
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Electro-Oxidation and Electro-Fenton Degradation of PFASs Using a Grid-Shaped Ti₄O₇ Magnéli-Phase Anode: Effect of Concentration and Evidence of Defluorination. [PDF]

Materials (Basel)
Daghfous S, Makhoul E, Petit E, Lesage G, Bechelany M, Bellakhal N, Cretin M.   +6 more
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Effect of biological and agricultural foaming agents on concrete waste for the preparation of porous ceramic materials. [PDF]

Sci Rep
Khattab RM, Abo-Almaged HH, Ali MM, Sadek HEH, Marzouk MA.   +4 more
europepmc   +1 more source