Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Effect of Hemoglobin Adsorption on Apparent Capacitance Density of Platinum Disk Nanoelectrode
A platinum disk nanoelectrode was prepared by sealing a platinum wire etched electrochemically in epoxy resin. Its apparent capacitance density (ACD) increased exponentially with its decreasing geometrical area.
Chengyin Wang, Yujing Chen, Xiaoya Hu*, Rong Guo
doaj +2 more sources
Compression Modulus and Apparent Density of Polymeric Excipients during Compression-Impact on Tabletability. [PDF]
Schönfeld BV, Westedt U, Wagner KG.
europepmc +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
In Morocco, the effects of climate change coupled with the degradation of soil resources are major factors limiting socio-economic development. Among these factors, intensive plowing practiced by Moroccan farmers causes depletion of soil organic matter ...
Malika LAGHROUR +3 more
doaj
Association of trabecular bone score and bone mineral apparent density with the severity of bone fragility in children and adolescents with osteogenesis imperfecta: A cross-sectional study. [PDF]
Ohata Y +10 more
europepmc +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Heat-insulating, fireproof and waterproof materials produced by recycling glass waste in microwave field [PDF]
The paper presents experimental results obtained in the manufacture of glass foams from packaging bottle glass waste, using the microwave energy. The glass foam as insulating material for construction is an advantageous alternative to existing building ...
Lucian PĂUNESCU +3 more
doaj
Studying the Physical Properties of System (Al-BuC) Composite [PDF]
The aim of this research is studying some physical properties (bulk density,apparent density, apparent porosity percentage, water absorption percentage) formetal matrix composite material.
doaj +1 more source

