Results 191 to 200 of about 2,577,258 (314)

Data from: Early-life diet specificity is associated with long-lasting differences in apparent survival in a generalist predator.xlsx

, 2023
Carina Nebel, Camilla Ekblad, Fabio Balotari‐Chiebao, Ida Penttinen, Torsten Stjernberg, Toni Laaksonen   +5 more
openalex   +2 more sources

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Population structure, apparent survival, and longevity of jaguars (Panthera onca) in the Bolivian Amazon: evidence from 22 years of monitoring

Guido Marcos Ayala, María Viscarra, Pedro Sarmento, Robert Benedict Wallace   +3 more
openalex   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Time-Dependent Bias and Prognostic Confounding in Exposure-Response Analysis of Targeted Therapies: Lessons from Sunitinib in Metastatic Renal Cancer. [PDF]

Clin Pharmacol Ther
Liu H, Friberg LE.
europepmc   +1 more source

Conditioning on pathological N stage doubles the apparent survival benefit of lymph node yield in resected gastric adenocarcinoma: a preregistered SEER cohort study

Wei Wei, Gao Quan, He Huang
openalex   +1 more source

A non‐invasive genetic approach for estimating the apparent survival rate of a long‐lived territorial raptor: a case study on the Golden Eagle Aquila chrysaetos [PDF]

Sébastien Waterlot, Christian Itty, Arzhela Hemery, Yoann Bunz, Cécile Kaerle, Guillaume Queney, Aurélien Besnard   +6 more
openalex   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Oncologic safety of sentinel lymph node-based nodal de-escalation in apparent uterine-confined endometrial cancer: a multicenter international cohort study. [PDF]

Front Oncol
Buda A, Capasso I, Mauro J, Perrone E, Mueller M, Fruscio R, Bruno V, Imboden S, Grassi T, Garcia-Pineda V, Tripodi E, Taskin S, Restaino S, Raimondo D, Capozzi VA, Papadia A, Siegenthaler F, Casarin J, Cucinella G, Vizza E, Zapardiel I, Vizzielli G, Taskiran C, Fanfani F.   +23 more
europepmc   +1 more source

Apparent Attraction as Asymmetric Relaxation in Constrained Field Dynamics: Selective trajectory survival without introducing new forces

Dmitri Deryabin
openalex   +1 more source