Results 81 to 90 of about 23,848 (309)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Apparitions of the Virgin Mary in contemporary fiction [PDF]

, 2006
iv, 64 p. A THESIS Presented to the Department of English and the Clark Honors College of the University of Oregon in partial fulfillment of the requirements for degree of Bachelor of Arts, Spring 2006.
Le Chevallier, Anne Marie
core   +1 more source

Apparitions Liv. 2

APPARITIONS LIV. 2 Apparitions Liv. 2 (1) Titelseite mit Stempel: Liszt-Museum Weimar: J 21 [b][2] (1) Noten (2) Advertising ( -
Schubert, Franz, Caraman, Liszt, Franz, Hofmeister, Friedrich   +3 more
core  

Apparitions in Alfred Schnittke’s Sonata No. 2 (quasi una Sonata) [PDF]

, 2016
Thesis (D.M.A.)--University of Washington, 2016-03This dissertation explores the apparitions present in Alfred Schnittke’s (1934-1998) Sonata No. 2 (quasi una Sonata) (1968).
Fitzpatrick, Luke
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Apparitions Liv. 1

APPARITIONS LIV. 1 Apparitions Liv. 1 (1) Titelseite imit Stempel: Liszt-Museum Weimar: J 21 [a] [2] (1) Noten (2) Advertising ( -
Rauzan, Clara von, Liszt, Franz, Hofmeister, Friedrich   +2 more
core  

Colloque "Apparitions fantastiques", Angers, 24-26 novembre

, 2011
COLLOQUE CRILA-CERIEC- CERLI 24-26 NOVEMBRE 2011 Apparitions fantastiques "Apparitions et disparitions dans la fiction brève (littérature et arts de l'image)" prog_crila_fantastiques297x420mm_20oct PROGRAMME : JEUDI 24 NOVEMBRE Accueil 13 h ...
Muriel Berthou Crestey
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Garden of the Apparitions, circa 1960

, 1960
Statue and altar in the garden of the apparitions in Beauraing, Belgium, circa 1960.https://ecommons.udayton.edu/imri_beauraing/1065/thumbnail ...

core   +1 more source