Results 181 to 190 of about 2,872,787 (410)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Luso-Brazilian Baroque Art: The role of Music in the Design of Architectural Elements in Portugal and its Repercussions in Bahia (Brazil)

open access: yesCuadernos de Música Iberoamericana
This article is an unpublished contribution that analyses the relationship between baroque architecture and music, with particular emphasis on the Portuguese capital, Lisbon, and other important cities in the country (Coimbra, Guimarães and Torres ...
Luzia Aurora Valeiro de Sousa Rocha
doaj   +1 more source

Appearance

open access: yes, 2015
A comprehensive chapter on appearance in Australian Civil ...
Colbran, SE   +2 more
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Impact of Display Sub-Pixel Arrays on Perceived Gloss and Transparency

open access: yesJournal of Imaging
In recent years, improvements in display image quality have made it easier to perceive rich object information, such as gloss and transparency, from images, known as shitsukan. Do the different display specifications in the world affect their appearance?
Midori Tanaka   +2 more
doaj   +1 more source

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