Results 121 to 130 of about 5,946,352 (283)
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Fitspiration content has become increasingly popular on visual social media platforms like RedNote (Xiaohongshu), presenting exercise, self-care, and body positivity as forms of health communication in the new media era. Despite these positive intentions,
Xu Wang, Jong-Mook Ahn, Chen Gong
doaj +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
The nature and functions of appearance‐related comparisons in body dysmorphic disorder
Appearance‐related comparisons (A‐RCs) in body dysmorphic disorder (BDD) are under researched despite their probable role in disorder maintenance. The present study therefore aimed to explore the nature (frequency, direction and automaticity), and functions of A‐RCs in BDD.
Mark A. Turner +2 more
openaire +2 more sources
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
In times of the rise of the “A4 waist” trend on social networks (SNs), concerns have been raised over appearance-related content’s adverse effects on body image and well-being in parasocial relationships. We conducted a survey on Chinese college students
Tong Yayun +4 more
doaj +1 more source
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
This study aimed to examine the mechanisms underlying the association between self-esteem and appearance anxiety, and whether these mechanisms differ by gender.
Anqi Shang, Han Bao
doaj +1 more source
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
In the digital age, social media has not only transformed the way individuals interact but has also become a significant platform for self-presentation, especially among young people.
Jinrui Tian, Boxuan Li, Ronghua Zhang
doaj +1 more source

