Results 121 to 130 of about 5,946,352 (283)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Mirror, motivate, or mislead? How fitspiration on RedNote affects health behaviors through appearance comparisons and self-esteem

open access: yesActa Psychologica
Fitspiration content has become increasingly popular on visual social media platforms like RedNote (Xiaohongshu), presenting exercise, self-care, and body positivity as forms of health communication in the new media era. Despite these positive intentions,
Xu Wang, Jong-Mook Ahn, Chen Gong
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The nature and functions of appearance‐related comparisons in body dysmorphic disorder

open access: yesScandinavian Journal of Psychology
Appearance‐related comparisons (A‐RCs) in body dysmorphic disorder (BDD) are under researched despite their probable role in disorder maintenance. The present study therefore aimed to explore the nature (frequency, direction and automaticity), and functions of A‐RCs in BDD.
Mark A. Turner   +2 more
openaire   +2 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Bothered More by Acquaintances’ Appearance than Celebrities’ on Social Networks: An Investigation of Comparison Targets’ Effect under Social Comparison Theory with a Chinese Student Sample

open access: yesSAGE Open
In times of the rise of the “A4 waist” trend on social networks (SNs), concerns have been raised over appearance-related content’s adverse effects on body image and well-being in parasocial relationships. We conducted a survey on Chinese college students
Tong Yayun   +4 more
doaj   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Self-esteem and appearance anxiety among Chinese college students: the roles of social media use and upward social comparison

open access: yesFrontiers in Psychology
This study aimed to examine the mechanisms underlying the association between self-esteem and appearance anxiety, and whether these mechanisms differ by gender.
Anqi Shang, Han Bao
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

The Impact of Upward Social Comparison on Social Media on Appearance Anxiety: A Moderated Mediation Model

open access: yesBehavioral Sciences
In the digital age, social media has not only transformed the way individuals interact but has also become a significant platform for self-presentation, especially among young people.
Jinrui Tian, Boxuan Li, Ronghua Zhang
doaj   +1 more source

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