Results 91 to 100 of about 891 (242)
Studia z Filologii Polskiej i SłowiańskiejThe article is devoted to the study of surnames of the historical territory of the Rivne region in Ukraine with the suffixes -uk-, -yuk-, -chuk- in the context of Ukrainian-Polish studies.
Світлана [Svitlana] Шийка [Shyika]
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
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ComicalitésThis article examines the representation of orality and linguistic variation in a corpus of so-called “banlieue” comics published between 2008 and 2023. Drawing on a comparison with the Multicultural Paris French corpus (Gadet et al.
Laurie Dekhissi
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Néologie sémantique et noms propres: le cas de l’antonomase
Neophilologica, 2007 The majority of linguists is currently of an opinion that proper names are asemantic. Disagreeing with this assumption, the author of the article, making use of an example of antonomasy, makes an attempt to prove that they have a semantic meaning.
Agnieszka Konowska
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Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
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DERIVATIVE OPPORTUNITIES OF THE UZBEK AND ENGLISH LANGUAGES IN THE SYSTEM OF FIGURATIVE PLACE NAMES [PDF]
, 2021 In this article the derivation of appellatives and toponyms of the Uzbek and English languages is discussed, as well as comparison of the formation of toponyms with the method of affixation is given.
Tashlanova, Nigora Djurayevna +1 more
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Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
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Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
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