Results 121 to 130 of about 62,567 (241)

Age‐Dependent Differences in Canakinumab Safety: A Comprehensive Pharmacovigilance Analysis Using the FAERS Database

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT While the efficacy of canakinumab, an anti‐interleukin‐1β monoclonal antibody, is well‐established, its safety profile, particularly across different age groups, remains inadequately explored. Using the FDA Adverse Event Reporting System (FAERS) database, this study evaluated postmarketing safety by analyzing adverse event (AE) reports from ...
Youyang Wang   +3 more
wiley   +1 more source

Risk factors associated with perforated acute appendicitis in geriatric emergency patients

open access: yes, 2018
Siriwimon Tantarattanapong, Nuraianee Arwae Department of Emergency Medicine, Songklanagarind Hospital, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, Thailand Objective: The aim of this study was to identify factors associated ...
Arwae N, Tantarattanapong S
core  

APPENDICITIS AND THE GYNECOLOGIST [PDF]

open access: yesJournal of the American Medical Association, 1917
About an inch and a half to the right of the navel and a trifle caudad, one will find on deep pressure a hypersensitive point in cases of chronic appendicitis of one of the four chief kinds. This tender point does not belong to cases of acute appendicitis.
openaire   +1 more source

Metformin as a Multifaceted Therapeutic Agent for Gastrointestinal Diseases: Mechanisms, Clinical Efficacy, and Future Directions

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT The high prevalence of gastrointestinal (GI) diseases and their significant impact on the quality of life require new therapeutic strategies. The development of novel therapeutic strategies should prioritize targeting the fundamental pathophysiological mechanisms underlying these diseases, including inflammation, cellular proliferation, and ...
Sayedeh Azimeh Hosseini   +7 more
wiley   +1 more source

The Use of a Computed Tomography Scan to Rule Out Appendicitis in Women of Childbearing Age is as Accurate as Clinical Examination: A Prospective Randomized Trial

open access: yes, 2007
Diagnosing appendicitis continues to be a difficult task for clinicians. The use of routine CT scan has been advocated to improve the accuracy of diagnosing appendicitis.
Lopez, Peter P   +5 more
core   +1 more source

Finding Minimum‐Cost Explanations for Predictions Made by Tree Ensembles

open access: yesSoftware: Practice and Experience, Volume 56, Issue 6, Page 615-642, June 2026.
ABSTRACT The ability to reliably explain why a machine learning model arrives at a particular prediction is crucial when used as decision support by human operators of critical systems. The provided explanations must be provably correct, and preferably without redundant information, called minimal explanations.
John Törnblom   +2 more
wiley   +1 more source

Az appendicitis acuta és egyéb akut hasi kórképek differenciáldiagnosztikája gyermekkorban

open access: yes, 2016
Gyermekkorban számos olyan kórkép fordul elő, amely akut hasi kórállapothoz vezet. A gyermekkorban az egyik leggyakoribb oka a Sürgősségi Betegellátó Osztály felkeresésének a hasi fájdalom fennállása. A hasi fájdalom kiváltó okának felderítése igen nehéz
Szaniszló, Réka
core  

Appendicitis tends to be complicated during the COVID-19 epidemic: A multicentre retrospective study

open access: yesSurgery Open Science
Background: In past studies, non-medical factors in the social-healthcare-patient triad associated with the prevalence of COVID-19 have led to delays in the presentation of patients with acute appendicitis and an increase in complications.
Macheng Lu   +8 more
doaj   +1 more source

Large Language Models for Explainable Medical Text Summarization: A Systematic Literature Review

open access: yesWIREs Data Mining and Knowledge Discovery, Volume 16, Issue 2, June 2026.
The graphical abstract highlights the three key aspects addressed in this review: the technical background of medical text summarization methods relevant to clinical decision support; the LLM background in providing context for its diagnosis and clinical significance; and clinical decision support with summarization and explainability in patient care ...
Aleka Melese Ayalew   +3 more
wiley   +1 more source

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