Results 41 to 50 of about 471,130 (310)

Insights into the renal pathophysiology in Hermansky‐Pudlak syndrome‐1 from urinary extracellular vesicle proteomics and a new mouse model

open access: yesFEBS Letters, EarlyView.
Hermansky‐Pudlak syndrome type 1 (HPS‐1) is a rare, autosomal recessive disorder with poorly understood renal involvement. Urinary extracellular vesicle (uEV) proteomics and a novel Hps1 mouse model reveal mitochondrial abnormalities and lipid accumulation in HPS‐1 kidney proximal tubule cells. Serum ApoA1 correlates with kidney function in our patient
Dawn M. Maynard   +7 more
wiley   +1 more source

Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren   +16 more
wiley   +1 more source

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini   +11 more
wiley   +1 more source

Amyand′s hernia

open access: yesJournal of Indian Association of Pediatric Surgeons, 2011
We report two children with Amyand′s hernia, where the appendices along with caecum were found within the left hernial sac, which were operated for obstructed inguinal hernia.
Kulwant Singh   +2 more
doaj   +1 more source

Documentary Appendix [PDF]

open access: yesItalian Politics, 2005
Il volume presenta i principali avvenimenti politici, istituzionali e sociali, che hanno contraddistinto l'anno 2004. L'appendice documentaria intende offrire al lettore il quadro demografico, economico, politico e sociale che fa da sfondo ai principali avvenimenti dell’anno 2004 trattati nel volume.
openaire   +7 more sources

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

open access: yesMolecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke   +12 more
wiley   +1 more source

Impact of molecular diagnostics and targeted cancer therapy on patient outcomes (MODIFY): a retrospective study of the implementation of precision oncology

open access: yesMolecular Oncology, EarlyView.
The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang   +3 more
wiley   +1 more source

AAPM‐RSS Medical Physics Practice Guideline 9.b: SRS‐SBRT

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract The purpose of this Medical Physics Practice Guideline (MPPG) is to describe the minimum level of medical physics support deemed prudent for the practice of linear‐accelerator, photon‐based (linac) stereotactic radiosurgery (SRS), and stereotactic body radiation therapy (SBRT) services.
Eileen Cirino   +9 more
wiley   +1 more source

The implications of the American Board of Radiology's decision to relinquish its specialty board designation on prospective authorized medical physicists (AMPs) and radiation safety officers (RSOs)

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract In order to independently supervise the medical use of byproduct material, physicists in the United States (US) must legally meet the qualifications defined by the Nuclear Regulatory Commission (NRC) in the 35th part of the tenth title of the Code of Federal Regulations (§ 10 CFR Part 35). The American Board of Radiology (ABR) relinquished its
Christopher J. Tien   +6 more
wiley   +1 more source

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