Results 71 to 80 of about 39,822 (344)
Dopaminergic and Non-Dopaminergic Value Systems in Conditioning and Outcome-Specific Revaluation [PDF]
, 2007 Animals are motivated to choose environmental options that can best satisfy current needs. To explain such choices, this paper introduces the MOTIVATOR (Matching Objects To Internal Values Triggers Option Revaluations) neural model.
Bullock, Daniel +2 more
core +1 more source
The elusive nature of the blocking effect: 15 failures to replicate [PDF]
, 2016 With the discovery of the blocking effect, learning theory took a huge leap forward, because blocking provided a crucial clue that surprise is what drives learning.
Alfei, Joaquín Matías +6 more
core +2 more sources
Advanced Science, EarlyView.Exclusive breastfeeding establishes a thermogenic memory in brown adipose tissue by activating the HIF1AN/AMPK/α‐ketoglutarate axis via milk‐derived extracellular vesicles enriched in miR‐125a‐5p. This programming preserves metabolic health, while αKG supplementation restores BAT function under mixed feeding, offering strategies to mitigate the ...
Ningxi Wu +13 more
wiley +1 more source
Advanced Science, EarlyView.The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang +15 more
wiley +1 more source
Boldness and natural behaviors in the African lion (Panthera leo): How are they related? [PDF]
, 2017 The African lion (Panthera leo) population is diminishing rapidly, approximately 43% since 1993 (Bauer et al., 2016. The species is currently listed as vulnerable by the IUCN (Bauer et al., 2016).
Kamyk, Courtney M
core +1 more source
Effects of dietary fibre on behaviour and satiety in pigs [PDF]
, 2008 During the past decades there has been considerable interest in the use of dietary fibre in both animal and human nutrition. In human subjects dietary fibre has been studied intensively for possible effects on body-weight management and health. In animal
Bolhuis, J.E. +3 more
core +2 more sources
Correlative Imaging Platform Linking Taste Cell Function to Molecular Identity
Advanced Science, EarlyView.A correlative imaging platform is developed to study how individual taste cells respond to different taste qualities. By linking cellular activity with molecular identity and environmental context, dual‐tuned taste cells capable of detecting both sweet and umami stimuli are identified.
Sungho Lee +6 more
wiley +1 more source
Conservation of the Lion: Preventing an Africa without the African Lion [PDF]
, 2018 The African lion (Panthera leo) population is diminishing rapidly, approximately 43 percent since 1993. The species is currently listed as vulnerable by the International Union for Conservation of Nature (IUCN).
Kamyk, Courtney
core +2 more sources
Corticosterone Regulates Both Naturally Occurring and Cocaine‐Induced Dopamine Signaling by Selectively Decreasing Dopamine Uptake [PDF]
, 2017 Stressful and aversive events promote maladaptive reward‐seeking behaviors such as drug addiction by acting, in part, on the mesolimbic dopamine system. Using animal models, data from our laboratory and others show that stress and cocaine can interact to
Baker, David A. +9 more
core +2 more sources
Hungry for Knowledge: Octopamine Signaling Regulates Hunger‐Enhanced Olfactory Learning
Advanced Science, EarlyView.Researchers demonstrate that hunger state facilitates both aversive and appetitive olfactory learning. Two distinct octopamine signaling pathways are involved in aversive or appetitive memory formation in the hunger state. And, hunger state also facilitates the formation of both types of memories via an evolutionarily conserved norepinephrine (the ...
Huijuan Zhao +14 more
wiley +1 more source