Results 131 to 140 of about 81,110 (302)

Applicant Entering

, 2018
Allentown Hospital School of Nursing. Applicant Beth Ann Winsko With Mother and Father Mr and Mrs John Winsko and sister Mary Jane Winsko.https://scholarlyworks.lvhn.org/lvhn-image-archives/1357/thumbnail ...
Lehigh Valley Health Network
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Declaration of Intention of George Drutt

, 1924
Declaration of Intention to become a citizen of the United States, as filled out and signed by: George Drutt (transcribed as George Drott) Applicant age: 52 Occupation: Farmer Country of Origin: Germany Date of Birth: 5th December 1877 Sailed to the ...

core   +1 more source

Too old to telework? Age but not gender shapes hiring biases across telework and office settings.

PLoS ONE
As teleworking becomes increasingly common in the post-pandemic workplace, recruiters may rely more on readily visible applicant characteristics (e.g., age and gender) when evaluating candidates, potentially triggering stereotype-based biases.
Kyriaki Fousiani, Sylvia Xu, Bibiana M Armenta Gutierrez, Chloe Sypes   +3 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Declaration of Intention of Hans Polter

, 1924
Declaration of Intention to become a citizen of the United States, as filled out and signed by: Hans Polter; form filled out with name Hans Potter Applicant age: 22 Occupation: Waiter Country of Origin:Germany Date of Birth: 16th July 1902 Sailed to the

core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Declaration of Intention of Herman Jacob Klein

, 1921
Declaration of Intention to become a citizen of the United States, as filled out and signed by: Herman Jacob Klein (signature: Jacob Herman Klein) Applicant age:54 Occupation: Tailor Country of Origin:Hungary Date of Birth: 8 December 1866 Sailed to the ...

core   +1 more source