Results 171 to 180 of about 407,207 (305)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Assessment of two feed additives consisting of <i>Lactiplantibacillus plantarum</i>ATCC PTA-6139 and <i>Lacticaseibacillus paracasei</i>ATCC PTA-6135 for all animal species (Pioneer Hi-Bred International, Inc). [PDF]

open access: yesEFSA J
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)   +17 more
europepmc   +1 more source

Applicability and Application of Microscopic Traffic Simulations [PDF]

open access: yes, 2013
Die Dynamik des Verkehrsflusses zeigt unterschiedliche, komplexe räumliche und zeitliche Muster. Ein bekanntes Phänomen ist beispielsweise der abrupte und plötzliche Abfall der Durchschnittsgeschwindigkeit auf einem Streckenabschnitt, der zu Stauungen führt. Zur Beurteilung der Qualität dreier ausgewählter Verkehrsmodelle (dem Nagel-Schreckberg Modell (
openaire   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Assessment of the feed additive consisting of coated granulated calcium iodate anhydrous for all animal species for the renewal of its authorisation (DOX-AL ITALIA SPA). [PDF]

open access: yesEFSA J
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)   +24 more
europepmc   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

The use of complex clinical trials: a regulatory review. [PDF]

open access: yesTrials
Nguyen Q, Kästel H, Hees K, Hofner B.
europepmc   +1 more source

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