Results 131 to 140 of about 2,181,891 (296)
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Primjena umjetnih neuronskih mreža pri identificiranju i vođenju procesa [PDF]
Kemija u Industriji, 2006 During the development of intelligent systems inspired by biological neural system, in the last two decades the researchers from various scientific fields have created neural networks for solving a series of problems from pattern recognition, prediction,
Jerbić, I., Bolf, N.
doaj
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Critical Public HealthTraditional teaching methods in respiratory medicine internships often fall short in cultivating trainees’ clinical reasoning and problem-solving skills.
Fei Wang +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Flexible Peak Shaving Technology for Coal-Fired Boilers Based on Intelligent Control
南方能源建设[Introduction] With the increasing demand for flexible peak shaving of thermal power units and the rapid development of information technology, thermal power enterprises are shifting from the traditional operation and management mode toward a cleaner ...
Minhang SONG, Hongyan YANG
doaj +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
A Computational Network Control Theory Analysis of Depression Symptoms
Personality NeuroscienceRumination and impaired inhibition are considered core characteristics of depression. However, the neurocognitive mechanisms that contribute to these atypical cognitive processes remain unclear.
Yoed N. Kenett +2 more
doaj +1 more source