Results 41 to 50 of about 69,616 (213)
Business Process Outsourcing [PDF]
Informatică economică, 2006 Business Process Outsourcing (BPO) is gaining widespread acceptance throughout the US, Europe, South America and Asia Pacific as the top executives of leading multinationals turn to outsourcing as a strategic management tool for improving corporate ...
Doina FOTACHE, Luminita HURBEAN
doaj
VNF Availability and SFC Sizing Model for Service Provider Networks
IEEE Access, 2020 This paper considers service provider network design with a view of meeting application availability. Our primary goal is to design a service provider network using disparate network components and low-availability Virtual Network Functions (VNFs) while ...
Sidharth Sharma +3 more
doaj +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Journal of Patient Experience, 2022 Patient-centered care and healthcare consumerism are the two most dominant ideas about the relationship between patients and providers in the United States.
Sung-Yeon Park PhD +4 more
doaj +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Research progress on continuous nursing model of stroke patients
Huli yanjiu, 2018 It reviewed the research progress on continuous nursing mode of stroke patients from the concept of continuous nursing,the concept of continuous nursing service for stroke,service object,provider,intervention strategy,nursing measures,application effect ...
朱伟, 蒋艳
doaj
Journal of Indonesian Tourism and Development Studies, 2020 Reservations can be interpreted as order transaction for place, ticket, or goods between business owners or service providers with consumers. In travel reservation, especially in Malang, people do some travel reservations manually.
Novita Rosyida, Agung Dwi Saputra
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