Results 51 to 60 of about 23,159,788 (290)

A Visual Analytics Approach for Station-Based Air Quality Data

open access: yesSensors, 2016
With the deployment of multi-modality and large-scale sensor networks for monitoring air quality, we are now able to collect large and multi-dimensional spatio-temporal datasets.
Yi Du   +6 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Checklist Approach for the Development of Educational Applications by Novice Software Developers

open access: yesIEEE Access, 2023
Innovation and challenges are significant factors that lead to the improvement in technology involving various sectors, including the educational field. New methods and techniques have been introduced in teaching and learning among learners and educators.
Norzila Ngadiman   +4 more
doaj   +1 more source

An Ontology for Software Patterns: Application to Blockchain-Based Software Development

open access: yes, 2023
Ensuring the quality of software design is usually a difficult task. In the blockchain field, the design of an application is particularly important as flaws can lead to critical vulnerabilities and cost overheads.To assist practitioners in this task, software patterns can be used (solutions to repeatable problems in a given context).Some blockchain ...
Six, Nicolas   +3 more
openaire   +3 more sources

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Integration of Safety Analysis in Model-Driven Software Development [PDF]

open access: yes, 2008
I Safety critical software requires integrating verification techniques in software development methods. Software architectures must guarantee that developed systems will meet safety requirements and safety analyses are frequently used in the assessment.
Fernández Briones, Javier   +3 more
core   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Development Effectiveness Overview (DEO) 2020: Executive Summary

open access: yes, 2020
The Development Effectiveness Overview (DEO) is an annual report produced by the IDB Group to share the results and impact of its work in Latin America and the Caribbean.
Inter-American Development Bank
core   +1 more source

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