Results 111 to 120 of about 1,094,052 (246)

Epigenetic Reactivation of TNFRSF19 Suppresses Mitophagy and Sensitizes Triple‐Negative Breast Cancer to Doxorubicin

Advanced Science, EarlyView.
TNFRSF19 is an epigenetically silenced regulator of mitophagy in triple‐negative breast cancer. TNFRSF19 deficiency activates the TGFBR1–SMAD3–PINK1 axis to promote mitophagy and confer doxorubicin resistance, whereas decitabine‐mediated restoration of TNFRSF19 suppresses mitophagy and enhances doxorubicin sensitivity, revealing a targetable epigenetic–
Shiyang Liu, Chenguang Liu, Weihong Zheng, Xiaofei Tong, Zhengwei Gui, Zonghong Lu, Sun Ieong, Lin Zhang   +7 more
wiley   +1 more source

OpenStats: how to combine statistics and research data management (RDM) to leverage efficient scientific data analysis by guided statistics. [PDF]

J Cheminform
Krämer K, Tremouilhac P, Mauz F, Grathwol C, Jung N, Bräse S.   +5 more
europepmc   +1 more source

Millisecond‐Scale Relaxation in Metastable HZO Ferroelectric Capacitors for Bio‐Inspired Temporal Computing

Advanced Electronic Materials, EarlyView.
Through the introduction of a niobium oxide layer into a hafnia ferroelectric capacitor stack, we build a memory device with a strong imprint effect. This imprint leads to a millisecond retention loss that can be tuned by the programming conditions that can be utilized as a scalable, analog hardware time constant for bio‐inspired temporal computing ...
Luca Fehlings, Thomas Mikolajick, Beatriz Noheda, Erika Covi   +3 more
wiley   +1 more source

Analog Weight Update Rule in Ferroelectric Hafnia, Using picoJoule Programming Pulses

Advanced Electronic Materials, EarlyView.
Resistive, ferroelectric synaptic weights based on BEOL‐compatible hafnia/zirconia nanolaminates are fabricated. Lateral downscaling the devices below 10 µm2 enables 20 ns programming with electrical pulses, dissipating ≤ 3 pJ. Experimental results show that final conductance state is set by pulse amplitude, and is largely independent of the initial ...
Alexandre Baigol, Nikhil Garg, Matteo Mazza, Yanming Zhang, Elisa Zaccaria, Wooseok Choi, Bert Jan Offrein, Laura Bégon‐Lours   +7 more
wiley   +1 more source

Mobile application software development

, 2019
The smartphone application industry has been on a steady rise all over the world, creating new jobs every year, in one of these companies I realised a 5-month internship in Sweden, developing a new feature for their app using React Native and Firebase. In this internship not only did I improved my programming skill but also gained invaluable insight on
openaire   +1 more source

ItemSight: Development of a Shiny Application for Simplified Item Analysis of Type A Multiple-Choice Questions. [PDF]

Cureus
Mondal H, Sarangi PK, Mondal S, Dhanvijay AD, Gayen RK, Mukhopadhyay A, Mishra R.   +6 more
europepmc   +1 more source

Experimental Demonstration of Temporally Aware Fault‐Tolerant Sensor Fusion Using Memristive Associative Learning

Advanced Electronic Materials, EarlyView.
In dynamic driving scenarios, the proposed approach ensures only temporally aligned sensor inputs to make driving decisions, preventing false activations. By enabling selective hardware‐level learning, it achieves fast, reliable responses under noisy conditions.
Kapil Bhardwaj, Ashfak Nehal, Dmitrii Semenov, Roman Sotner, Sayani Majumdar   +4 more
wiley   +1 more source

Integrating stakeholder perspectives in the co-design of medical device software to monitor Parkinson's disease symptoms- A case-study. [PDF]

MethodsX
Raut RA, Polus B, Ngo QC, Pah ND, Clay-Williams R, Kumar DK.   +5 more
europepmc   +1 more source

Drift Reduction in 2D PtSe2 Piezoresistive Pressure Sensors Through an On‐Chip Wheatstone Bridge

Advanced Electronic Materials, EarlyView.
Drift is a major source of error affecting the accuracy and repeatability of sensors. A Wheatstone bridge (WSB) enables high sensitivity, accuracy, and the elimination of common‐mode drift. We apply the WSB concept to highly sensitive piezoresistive pressure sensors made with two‐dimensional layered platinum diselenide transducers.
Ragini Gupta, Sebastian Lukas, Nico Rademacher, Michael Gross, Nikolas Dominik, Georg S. Duesberg, Max C. Lemme   +6 more
wiley   +1 more source

A digital twin approach for transforming prescription drug labeling. [PDF]

Front Pharmacol
Kimko H, Kimko E, Venkatapurapu SP.
europepmc   +1 more source