Results 121 to 130 of about 3,547,224 (332)
Emerging from the MIST: A Connector Tool for Supporting Programming by Non-programmers [PDF]
, 2010 Software development is an iterative process. As user re-quirements emerge software applications must be extended to support the new requirements. Typically, a programmer will add new code to an existing code base of an application to provide a new ...
Bhatia, Saurabh +3 more
core +1 more source
Advanced Science, EarlyView.Phosphorylation of Optineurin by TBK1 induces the formation of filaments that condensate upon binding to linear polyubiquitin. Membrane‐anchored LC3 partitions into these condensates, suggesting that phase separation of filamentous Optineurin with ubiquitylated cargo promotes the sequestration of cargo and its subsequent alignment with LC3‐positive ...
Maria G. Herrera +10 more
wiley +1 more source
Advanced Science, EarlyView.Genetic and pharmacological inhibition of SLC11A1 functioning as an H+/Fe2+ antiporter–mediated lysosomal iron accumulation in microglia promotes lysosomal lumen acidification, increases CTSD expression, enhances lysosomal myelin debris uptake and degradation, and promotes repair following white matter stroke. ABSTRACT White matter stroke (WMS) results
Lingling Qiu +11 more
wiley +1 more source
Software development on thermoelectrics applications
, 2004 The main objective of this project is to develop a platform-independent and interactive software application, which is capable of selecting thermoelectric module(s) available from different manufacturers. And also to provide steps required for an optimum design of a complete Thermoelectric Cooling System by exploring the important thermoelectric ...
openaire +1 more source
Advanced Science, EarlyView.Single‐cell sequencing reveals stress‐programmed immune states driving TNFα–TNFR2–mediated Treg activation and therapy resistance in breast cancer, while targeting this axis restores antitumor immunity. ABSTRACT The tumor microenvironment (TME) harbors diverse immune cell states that shape therapeutic outcomes in breast cancer.
Zhibo Shao +18 more
wiley +1 more source
Development of a Controlled Vocabulary and Software Application to Analyze Fruit Shape Variation in Tomato and Other Plant Species [PDF]
, 2006 Marin T. Brewer +5 more
openalex +1 more source
Firing Room Remote Application Software Development [PDF]
The Engineering and Technology Directorate (NE) at National Aeronautics and Space Administration (NASA) Kennedy Space Center (KSC) is designing a new command and control system for the checkout and launch of Space Launch System (SLS) and future rockets ...
Liu, Kan
core +1 more source
Targeting DNA‐LNPs to Endothelial Cells Improves Expression Magnitude, Duration, and Specificity
Advanced Science, EarlyView.Attaching antibodies against endothelial cell surface proteins redirects the delivery and expression of DNA‐lipid nanoparticles to organs of interest. Our targeted nanoparticles enable organ‐selective DNA expression in the endothelium of the lungs, brain, or spleen, providing a therapeutic platform for dozens of endothelial‐centric diseases.
Nicolas Marzolini +24 more
wiley +1 more source
Research on Application Value of Computer Software Development in Java Programming Language
, 2020 Yangyang Jiang
openalex +1 more source
Software Implemented Fault-Tolerant (SIFT) user's guide [PDF]
Program development for a Software Implemented Fault Tolerant (SIFT) computer system is accomplished in the NASA LaRC AIRLAB facility using a DEC VAX-11 to interface with eight Bendix BDX 930 flight control processors.
Baltrus, D. W. +2 more
core +1 more source