Results 91 to 100 of about 26,287,377 (329)

Baseline Neuroinflammation Stratifies TSPO‐PET Response to Disease‐Modifying Therapy in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate which baseline clinical and imaging characteristics best predict TSPO‐PET‐measurable reduction in glial activation following treatment of multiple sclerosis (MS), to utilize this information for designing more efficient biomarker‐based clinical trials targeting glial activation.
Marlene T. Morch, Markus Matilainen, Giulia N. Baldrighi, Marjo Nylund, Maija Saraste, Laura Airas   +5 more
wiley   +1 more source

Data‐Driven SuStaIn Model of Disability Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether ordinal Subtype and Stage Inference (SuStaIn) applied to routine ALSFRS‐R item scores can identify reproducible disability progression patterns in amyotrophic lateral sclerosis (ALS) and provide clinically meaningful staging.
Giammarco Milella, Veria Vacchiano, Vittorio Velucci, Stefano Zoccolella, Rocco Liguori, Giovanni Defazio   +5 more
wiley   +1 more source

From Bench to Brain: A Metadata-driven Approach to Research Data Management in a Collaborative Neuroscientific Research Center

Data Science Journal
Research data management (RDM) is key to fast and effective cooperation in collaborative research projects, especially when several scientific disciplines are involved.
Marlene Pacharra, Tobias Otto, Nina Olivia Caroline Winter   +2 more
doaj   +1 more source

"Leagile" software development: An experience report analysis of the application of lean approaches in agile software development

Journal of Systems and Software, 2012
In recent years there has been a noticeable shift in attention from those who use agile software development toward lean software development, often labelled as a shift "from agile to lean".
Xiao-Feng Wang, Kieran Conboy, Oisín Cawley   +2 more
semanticscholar   +1 more source

Financing the Future with the IDB Group [PDF]

, 2019
Mobilizing resources is critical to the implementation of the 2030 Agenda and multilateral development banks in particular have been called upon to crowd-in additional financing for the Sustainable Development Goals (SDGs).
Inter-American Development Bank
core   +1 more source

Clinical Impact of MGMT Promoter Methylation in IDH‐Mutant Gliomas: Influence of Threshold Selection and Clinical Confounding

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background The clinical relevance of MGMT promoter methylation in IDH‐mutant gliomas remains controversial in the era of molecular classification. We aimed to systematically evaluate its clinical relevance by integrating quantitative assessment, cutoff exploration, and adjustment for clinical confounding.
Haihui Jiang, Linxi Cao, Xiaodong Chen, Siqi Tong, Qinghui Zhu, Jun Yang, Song Lin, Yong Cui   +7 more
wiley   +1 more source

Integrating AI-based adaptive learning into the flipped classroom model to enhance engagement and learning outcomes

Computers and Education: Artificial Intelligence
This study explores the integration of the AI-powered adaptive learning system within the flipped classroom model and discusses programming education.
Jozsef Katona, Klara Ida Katonane Gyonyoru   +1 more
doaj   +1 more source

Geneious Basic: An integrated and extendable desktop software platform for the organization and analysis of sequence data

Bioinform., 2012
Summary: The two main functions of bioinformatics are the organization and analysis of biological data using computational resources. Geneious Basic has been designed to be an easy-to-use and flexible desktop software application framework for the ...
M. Kearse, R. Moir, Amy Wilson, S. Stones-Havas, M. Cheung, S. Sturrock, S. Buxton, A. Cooper, S. Markowitz, Chris Duran, T. Thierer, Bruce Ashton, P. Meintjes, A. Drummond   +13 more
semanticscholar   +1 more source

Perceived Impacts and Predictors of Cannabis Products Used by Patients with Rheumatologic Conditions in Alberta, Canada: A Multivariable Analysis of Cross‐Sectional Survey Data

Arthritis Care &Research, EarlyView.
Objective This study aimed to characterize cannabis product choices (cannabinoid content and formulation) among patients with rheumatologic conditions and their associations with patient factors, patient‐reported perceived side effects, and positive impacts.
Susan Zhang, Samuel A.J. Lowe, Frank Sun, Allyson Jones, Tarek Turk, Joanne Olson, Pauline Paul, Shelby Yamamoto, Linda Kolewaski, Elaine Yacyshyn, Cheryl A. Sadowski   +10 more
wiley   +1 more source

Distinct Systemic Sclerosis Phenotypes Related to Ethnicity: An Opportunity to Personalize Care?

Arthritis Care &Research, EarlyView.
Objective The objective is to describe and compare demographic, clinical, and serological characteristics of patients with systemic sclerosis (SSc) according to ethnic background. Methods Participants enrolled in the Canadian Scleroderma Research Group cohort who self‐identified to a single ethnicity group were included.
Danick Goulet, Camille Guertin, Maggie Larché, Isabelle Ferdinand, Marie Hudson, May Y. Choi, Mohammed Osman, Janet Pope, Carter Thorne, Murray Baron, Sasha Bernatsky, Sabrina Hoa   +11 more
wiley   +1 more source