Results 111 to 120 of about 24,564,681 (283)

Xamarin Cross-platform Application Development

open access: yes, 2014
Xamarin Cross-platform Application Development" is an end-to-end walk-through tutorial on developing applications for both iOS and Android. It offers clear and detailed explanations of each stage in the process, making it easier for you to master the ...
Peppers, Jonathan
core  

KLF5 Downregulation Links Impaired BNIP3‐Mediated Mitophagy to Inflammatory Valve Remodeling in Calcific Aortic Valve Disease

open access: yesAdvanced Science, EarlyView.
In human CAVD, KLF5 is reduced in VIC‐rich regions and remodeling/stress‐associated VIC states. In VICs, KLF5 sustains BNIP3 promoter activity and BNIP3‐mediated mitophagy, thereby limiting cytosolic mtDNA accumulation. KLF5 loss weakens mitochondrial quality control and enhances mtDNA‐sensitive STING/NF‐κB/NLRP3 inflammatory signaling under osteogenic
Jin‐Hui Bian   +13 more
wiley   +1 more source

RTC-DETR234: Real-Time CBAM Detection Transformer 234—Diagnostic Detection of Band Sawtooth and Fractures

open access: yesApplied Sciences
In industrial production processes, accurate and fast detection of band sawtooth deformations is of critical importance. Traditional detection approaches are not sustainable at industrial scale due to their high human attention requirements and low ...
Oğuzhan Uymaz   +3 more
doaj   +1 more source

Nickel Intercalation in Epitaxial Graphene on SiC(0001): A Novel Platform for Engineering Two‐Dimensional Heterostructures

open access: yesAdvanced Science, EarlyView.
Ni‐intercalated graphene on SiC is achieved through a scalable colloidal nanoparticle deposition route. 2D heterostructures show preserved graphene band structure, stable under ambient conditions, and robust interfacial magnetism. Intercalated 2D Ni represents a promising candidate for next‐generation spintronic devices and is a scalable pathway to ...
Ylea Vlamidis   +7 more
wiley   +1 more source

Epigenetic Reactivation of TNFRSF19 Suppresses Mitophagy and Sensitizes Triple‐Negative Breast Cancer to Doxorubicin

open access: yesAdvanced Science, EarlyView.
TNFRSF19 is an epigenetically silenced regulator of mitophagy in triple‐negative breast cancer. TNFRSF19 deficiency activates the TGFBR1–SMAD3–PINK1 axis to promote mitophagy and confer doxorubicin resistance, whereas decitabine‐mediated restoration of TNFRSF19 suppresses mitophagy and enhances doxorubicin sensitivity, revealing a targetable epigenetic–
Shiyang Liu   +7 more
wiley   +1 more source

Development of an AI IoT-based smart system to support improved beach visitor safety

open access: yesMatrix: Jurnal Manajemen Teknologi dan Informatika
The high rate of sea accidents at Indonesian coastal tourist destinations, such as those occurring at Parangtritis and Pangandaran beaches, underscores the limitations of conventional safety systems that rely on manual surveillance. The objective of this
Kusrini Kusrini   +4 more
doaj   +1 more source

Software Agent Reusability Mechanism at Application Level [PDF]

open access: yes, 2013
The usage of already available software agents plays a vital role in the process of development of application specific software. This reuse also leads to software development cost benefits as well as may ensure the timely delivery.
Deepti Aggarwal, Aarti Singh
core  

High‐Performance Violet Phosphorene‐Based Device via Tellurium Doping‐Induced Contact Resistance Reduction

open access: yesAdvanced Science, EarlyView.
Tellurium substitution for phosphorus in violet phosphorus significantly reduces contact resistance, enhancing FET performance under ambient conditions. ABSTRACT Two‐dimensional materials have attracted much attention in various research fields. The phosphorene structures with various allotropes, another type of elemental 2D materials after graphene ...
Zhuorui Wen   +12 more
wiley   +1 more source

SIRT7‐Mediated H2BK120 Succinylation Drives Aberrant Mitophagy in Sepsis‐Associated Cognitive Dysfunction

open access: yesAdvanced Science, EarlyView.
Sepsis triggers hippocampal SIRT7 loss, promoting histone H2B succinylation and activation of the PD‐1/PD‐L1–PINK1 axis. This metabolic‐epigenetic cascade drives aberrant mitophagy and neuronal injury, ultimately causing cognitive deficits. Targeting SIRT7‐dependent succinylation offers a potential strategy to protect brain function during sepsis ...
Na Meng   +12 more
wiley   +1 more source

DATABASE DEVELOPMENT LIFE CYCLE [PDF]

open access: yes
A software development life cycle model (SDLC) consists of a set of processes (planning, requirements, design, development, testing, installation and maintenance) defined to accomplish the task of developing a software application that is functionally ...
Morgan D. Monger   +2 more
core  

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