Results 51 to 60 of about 24,564,681 (283)
Impact Evaluation of the Business Development Program for the Software Industry in Uruguay [PDF]
, 2010 The purpose of this impact evaluation is to assess the success of the Business Development Program for the Software Industry in Uruguay in achieving and sustaining results over time.
Inter-American Development Bank
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Molecular Oncology, EarlyView.This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
Molecular Oncology, EarlyView.CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source
Impact Evaluation of the Business Development Program for Uruguay\u27s Software Industry [PDF]
, 2010 This presentation discusses the impact of the Program for the Support of the Software Sector in Uruguay. It includes a brief summary of the project, the program outputs and outcomes, the key findings of the impact evaluation, and lessons and ...
Inter-American Development Bank
core +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Inter-American Development Bank Annual Report 2021: Financial Statements
, 2022 This report is the second of two volumes which together constitute the Inter-American Development Bank\u27s 2021 Annual Report. This report contains the management\u27s discussion and analysis of the Bank\u27s ordinary capital and financial ...
Inter-American Development Bank
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FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
FEBS Open Bio, EarlyView.Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
Coaching the Application of Agile Software Development [PDF]
, 2007 The success of agile software development has drawn attention to coaching as an alternative management style. In this paper, we argue that coaching, with its focus on trustful relationships, empathetic communication, mental models, and experiential learning, is suitable to facilitate the sustainable application of agile software development.
openaire +2 more sources
Inter-American Development Bank Sustainability Report 2019 [PDF]
, 2020 Sustainability is a core element of the IDBs work. Long-term economic growth, and the reduction of poverty and inequality in Latin America and the Caribbean depend on development that is economically, financially, environmentally, socially, and ...
Inter-American Development Bank
core +1 more source