Results 181 to 190 of about 17,818,434 (195)

Pharmacogenomic profiling of the efficacy of gemcitabine monotherapy in metastatic pancreatic cancer: Subgroup analysis of the GENESECT study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim In the GENESECT study, no significant gemcitabine (GEM) metabolism‐related germline genetic polymorphisms (GPs) were identified because approximately 70% of patients received combination therapy with nab‐paclitaxel, which has metabolic pathways different from GEM.
Takashi Yokokawa   +21 more
wiley   +1 more source

Impact of Salt Stress on Phytochemical Changes and Biological Activities of Quinoa Leaf Extracts In Vitro and In Silico. [PDF]

open access: yesPharmaceuticals (Basel)
Arraouadi S   +7 more
europepmc   +1 more source

Machine Learning Models of Phase Contrast Images Predict Efficiency of Human Pluripotent Stem Cell Differentiation to Cardiomyocytes

open access: yesBiotechnology and Bioengineering, EarlyView.
Human pluripotent stem cells were differentiated to cTnT+ cardiomyocytes and imaged throughout the process using phase contrast. We predicted differentiation efficiency (cTnT+ area) from phase contrast and compared model performance with a live‐cell cTnT‐GFP reporter.
Austin K. Feeney   +6 more
wiley   +1 more source

Translating Blue Light Stimulation From Batch to Perfusion: Process and Intracellular Metabolic Analysis

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Improving cell‐specific productivity remains a central objective in biopharmaceutical manufacturing. In this study, the effect of blue light illumination on IgG1‐producing CHO DP‐12 cells was systematically evaluated across batch, fed‐batch, and perfusion cultivations in controlled 3 L bioreactor systems.
Stefanie Föller   +2 more
wiley   +1 more source

External Acoustic Meatus Approach for Ultrasonographic Evaluation of the Temporomandibular Joint: An Anatomical Validation and Proof‐of‐Concept Study

open access: yesClinical Anatomy, EarlyView.
ABSTRACT Temporomandibular disorders (TMD) represent a public health problem, affecting 31% of adults and the elderly and 11% of children and adolescents. Interest is growing in using ultrasound to evaluate the temporomandibular joint (TMJ). However, researchers need to standardize a reliable method.
Rossella Alberti   +10 more
wiley   +1 more source

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