Results 131 to 140 of about 7,377,675 (253)

Dating Applications as HIV Prevention Ecosystems in the Era of Digital Sexual Networks. [PDF]

Infect Dis Rep
De Maria F, Fusco P, Russo A.
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Multimedia Tools and Applications

Multimedia Tools and Applications publishes original research articles on multimedia development and system support tools, and case studies of multimedia applications. Experimental and survey articles are appropriate for the journal.
Marco Roccetti
core   +1 more source

RETRACTION: Is Telephysiotherapy an Option for Improved Quality of Life in Patients With Osteoarthritis of the Knee? [PDF]

Int J Telemed Appl
Telemedicine And Applications IJO.
europepmc   +1 more source

Hazardous material transportation safety and security field operational test final detailed test plans : executive summary

DTFH61-96-C-00098, Task 9851The objective of this Hazardous Material (HazMat) Transportation Safety and Security Field Operational Test (FOT) Final Detailed Test Plans evaluation is to measure the impact of technology solutions on the safety, security ...
Science Applications International Corporation
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Association Between Smartphone Application Diversity and Occupational Participation Among Community-Dwelling Older Adults: A Cross-Sectional Study. [PDF]

Scand J Occup Ther
Shimokihara S, Yokoyama K, Ihira H, Matsuzaki-Kihara Y, Mizumoto A, Tashiro H, Saito H, Makino K, Katsuura S, Kobayashi M, Shimada K, Yama K, Miyajima R, Sasaki T, Ikeda N.   +14 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Artificial Intelligence in Orthopedics: Global Research Trends and Emerging Applications. [PDF]

Orthop Rev (Pavia)
Bosh L, Gadikota P, Viswanath O, Ganti L.   +3 more
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source