Generative artificial intelligence in lung cancer care: current applications, challenges, and future directions. [PDF]
Zhang W +9 more
europepmc +1 more source
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Efficacy and Safety of 60 W Versus 90 W, 4-s Radiofrequency Applications to the Esophagus-Adjacent Left Atrial Posterior Wall During Pulmonary Vein Isolation: A Pilot Study. [PDF]
Okamatsu H +9 more
europepmc +1 more source
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Valorization of Soybean Meal: From Conventional Feed Ingredient to Multifunctional Protein Resource for Food, Biotechnology, and Sustainable Applications. [PDF]
Nguyen OTK, Nargotra P, Liu YC, Kuo CH.
europepmc +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
MXenes at the Immune Interface: A Perspective on Influence of Physicochemical Design in Immunomodulation. [PDF]
Rafieerad A, Saleth LR, Dhingra S.
europepmc +1 more source
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
mHealth Applications in the Assessment of Musculoskeletal Pain in Menopausal Women: Protocol for a Scoping Review. [PDF]
Buttenham O, McCreesh K, Crowley K.
europepmc +1 more source

