Results 41 to 50 of about 587,398 (223)

Dynamics of growth factor production in monolayers of cancer cells and evolution of resistance to anticancer therapies [PDF]

, 2013
Tumor heterogeneity is well documented for many characters, including the production of growth factors, which improve tumor proliferation and promote resistance against apoptosis and against immune reaction.
Achilles, Aktipis, Aktipis, Amit, André, Archetti, Archetti, Archetti, Archetti, Archetti, Archetti, Armitage, Ashley, Axelrod, Basanta, Basanta, Basanta, Basanta, Basanta, Boza, Byrne, Cairns, Charles, Chuang, Crespi, Crespi, Dexter, Dingli, Durrett, Eungdamrong, Fisher, Foster, Frank, Gatenby, Gatenby, Gerstung, Gonzalez-Garcia, Greaves, Hanahan, Hardin, Hauert, Hemker, Ifti, Iwasa, Jouanneau, Knudson, Lambert, Maley, Marusyk, Maynard Smith, Mendes, Merlo, Motro, Nagy, Nordling, Nowell, Ohtsuki, Pacheco, Palfrey, Pepper, Perc, Rapoport, Ricard, Sugden, Tomlinson, Tomlinson, Traulsen, Traulsen   +67 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Photoswitching Conduction in Framework Materials

Advanced Functional Materials, EarlyView.
This mini‐review summarizes recent advances in state‐of‐the‐art proton and electron conduction in framework materials that can be remotely and reversibly switched on and off by light. It discusses the various photoswitching conduction mechanisms and the strategies employed to enhance photoswitched conductivity.
Helmy Pacheco Hernandez, Stefan Hecht, Wolfgang Wenzel, Lars Heinke, Mariana Kozlowska   +4 more
wiley   +1 more source

A New Rational Algorithm for View Updating in Relational Databases

, 2014
The dynamics of belief and knowledge is one of the major components of any autonomous system that should be able to incorporate new pieces of information.
Behrend, Andreas, Delhibabu, Radhakrishnan   +1 more
core   +1 more source

Neuro-fuzzy knowledge processing in intelligent learning environments for improved student diagnosis [PDF]

, 2005
In this paper, a neural network implementation for a fuzzy logic-based model of the diagnostic process is proposed as a means to achieve accurate student diagnosis and updates of the student model in Intelligent Learning Environments.
Grigoriadou, M., Magoulas, George D., Samarakou, M., Stathacopoulou, R.   +3 more
core   +2 more sources

Photon Avalanching Nanoparticles: The Next Generation of Upconverting Nanomaterials?

Advanced Functional Materials, EarlyView.
This Perspective outlines the mechanistic foundations that enable photon‐avalanche (PA) behavior in lanthanide nanomaterials and contrasts them with emerging application spaces and forward‐looking design strategies. By bridging threshold engineering, energy‐transfer dynamics, and materials engineering, we provide a coherent roadmap for advancing the ...
Kimoon Lee, Yunseo Kim, Hyeong‐ku Jo, Dongjoon Yoon, Byeonghyeok Im, WonJeong Yu, Eui‐Rim On, Changhwan Lee   +7 more
wiley   +1 more source

A collective intelligence model for swarm robotics applications

Nature Communications
Swarm intelligence models represent a powerful tool to address complex tasks by multi-agent systems, although they are rarely used in practical applications as decentralized cooperation logic.
Alessandro Nitti, Marco D. de Tullio, Ivan Federico, Giuseppe Carbone   +3 more
doaj   +1 more source

Fuzzy-logic-based control, filtering, and fault detection for networked systems: A Survey [PDF]

, 2015
This paper is concerned with the overview of the recent progress in fuzzy-logic-based filtering, control, and fault detection problems. First, the network technologies are introduced, the networked control systems are categorized from the aspects of ...
Dong, H, He, X, Hu, J, Quqiang, L, Shen, B, Wang, Z, Wei, G   +6 more
core   +3 more sources

Toward Stable Multivalent Metal Batteries: Understanding the Interfacial Chemistry for Magnesium and Calcium Metal Anodes

Advanced Functional Materials, EarlyView.
Interphase chemistry governs the stability of multivalent metal batteries. We summarize state‐of‐the‐art developments in calcium and magnesium metal batteries by focusing on the correlation among electrolytes, interphase layers, and the electrochemical performance of corresponding metal anodes.
Huijun Lin, Qi Meng, Juncai Long, Chuheng Cao, Zheng‐Long Xu   +4 more
wiley   +1 more source