Results 31 to 40 of about 34,311 (304)

Bilevel programming methods for computing single-leader-multi-follower equilibria in normal-form and polymatrix games

EURO Journal on Computational Optimization, 2020
The concept of leader-follower (or Stackelberg) equilibrium plays a central role in a number of real-world applications bordering on mathematical optimization and game theory.
Nicola Basilico, Stefano Coniglio, Nicola Gatti, Alberto Marchesi   +3 more
doaj   +1 more source

Developments in linear and integer programming

, 2002
In this review we describe recent developments in linear and integer (linear) programming. For over 50 years Operational Research practitioners have made use of linear optimisation models to aid decision making and over this period the size of problems ...
Darby-Dowman, K, Wilson, J M
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Error bounds in mathematical programming

, 1997
Originated from the practical implementation and numerical considerations of iterative methods for solving mathematical programs, the study of error bounds has grown and proliferated in many interesting areas within mathematical programming.
Pang, Jong-Shi, Jong-Shi Pang
core   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

A Mathematical Model of Operation of a Semi-Trailer Tractor Powertrain

Communications, 2022
The mathematical modelling is an inseparable part of mechanical engineers' activities. It is applied in design, optimization, verifying, as well as modifying of products.
Ján Dižo, Miroslav Blatnický, Rafał Melnik, Oleksandr Kravchenko   +3 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

A General Inertial Projection-Type Algorithm for Solving Equilibrium Problem in Hilbert Spaces with Applications in Fixed-Point Problems

Axioms, 2020
A plethora of applications from mathematical programming, such as minimax, and mathematical programming, penalization, fixed point to mention a few can be framed as equilibrium problems.
Nopparat Wairojjana, Habib ur Rehman, Manuel De la Sen, Nuttapol Pakkaranang   +3 more
doaj   +1 more source

Exploiting the Abstract Calculus Pattern for the Integration of Ordinary Differential Equations for Dynamics Systems: An Object-Oriented Programming Approach in Modern Fortran

Dynamics, 2023
This manuscript relates to the exploiting of the abstract calculus pattern (ACP) for the (numerical) solution of ordinary differential equation (ODEs) systems, which are ubiquitous mathematical formulations of many physical (dynamical) phenomena.
Stefano Zaghi, Cristiano Andolfi
doaj   +1 more source