Results 31 to 40 of about 166,556,508 (284)
penalty methods and some applications of mathematical programming [PDF]
, 1975 The problem of minimization of the convex function F : Rn → R on the convex solid compact set Ω ⊂ Rn is under consideration.
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Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
EURO Journal on Computational Optimization, 2020 The concept of leader-follower (or Stackelberg) equilibrium plays a central role in a number of real-world applications bordering on mathematical optimization and game theory.
Nicola Basilico +3 more
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Reformulation in mathematical programming: An application to quantum chemistry
Discrete Applied Mathematics, 2009 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Leo Liberti +3 more
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Developments in linear and integer programming [PDF]
, 2002 In this review we describe recent developments in linear and integer (linear) programming. For over 50 years Operational Research practitioners have made use of linear optimisation models to aid decision making and over this period the size of problems ...
Darby-Dowman, K, Wilson, J M
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Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
A Mathematical Model of Operation of a Semi-Trailer Tractor Powertrain
Communications, 2022 The mathematical modelling is an inseparable part of mechanical engineers' activities. It is applied in design, optimization, verifying, as well as modifying of products.
Ján Dižo +3 more
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Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Axioms, 2020 A plethora of applications from mathematical programming, such as minimax, and mathematical programming, penalization, fixed point to mention a few can be framed as equilibrium problems.
Nopparat Wairojjana +3 more
doaj +1 more source