Results 21 to 30 of about 22,919 (246)
First-principles prediction of magnetically ordered half-metals above room temperature
Half-metallicity (HM) offers great potential for engineering spintronic applications, yet only few magnetic materials present metallicity in just one spin channel.
Muhammad Atif Sattar +3 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Digital image-based determination of aggregate and rock gradation has been only limitedly addressed in the existing literature despite its considerable potential to transform conventional material characterization practices in civil engineering.
Muhammet Karabulut +2 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Interaction effect of zeolite and salt stress in reproductive stage of four canola varieties [PDF]
Introduction Canola (Brassica napus L.) is one of the most important plants to produce edible oil in Iran and in the world and also one of the negative factors for crop plants is the relative salinity of irrigation water in some areas of Iran.
Vahid Esmaeilzadeh +4 more
doaj +1 more source
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Safety analysis of geothermal water recharge coupled with CO2 geological storage system
Objective In well-trapped hydrothermal geothermal reservoirs, the research on injecting CO2 into reservoirs simultaneously with recharge water is carried out, which has both economic and environmental benefits for carbon sequestration.
Yanan LUO +4 more
doaj +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
How to best freeze liver samples to perform the in vivo mammalian alkaline comet assay
The comet assay is widely used nowadays as its main applications include genotoxicity testing, human biomonitoring, DNA repair studies, environmental biomonitoring and clinical studies.
José Manuel Enciso Gadea
doaj +1 more source

