Results 161 to 170 of about 87,331 (292)

Carbon Nanotube Hydrogels Reveal Threshold‐Dependent Regulation of Neuroblastoma Cell Growth and Maturation by Mechanical and Chemical Factors

Small Science, Volume 5, Issue 11, November 2025.
Poly(vinyl alcohol)/carbon nanotube (PVA/CNT) hydrogels with unprecedented CNT loading (75% w/w) were engineered as 3D scaffolds for nerve regeneration. By tuning Young's modulus (YM), CNT concentration, and pore size, distinct thresholds controlling cell coverage were identified. Optimized scaffolds achieved > 70% coverage and upregulated β‐3‐tubulin (
Bahaa Daou, Maurizio Prato, Sonia Alonso‐Martín, Nuria Alegret   +3 more
wiley   +1 more source

Uncovering Phenotypes in Sensorineural Hearing Loss: A Systematic Review of Unsupervised Machine Learning Approaches. [PDF]

Ear Hear
Dimitrov L, Barrett L, Chaudhry A, Muzaffar J, Lilaonitkul W, Mehta N.   +5 more
europepmc   +1 more source

Generating Logical Architectures from SysML Behavior Models

Systems Engineering, Volume 28, Issue 6, Page 762-778, November 2025.
ABSTRACT Modeling solution‐neutral operating principles of system features as SysML behavior models enable systems engineers to specify reusable product features for a variety of similar products and to specify and document a product's functionality in an easy‐to‐understand manner.
Christian Granrath, Christopher Kugler, Judith Michael, Bernhard Rumpe, Louis Wachtmeister   +4 more
wiley   +1 more source

Formalized aspect-oriented misuse case for specifying crosscutting security threats and mitigations. [PDF]

PLoS One
Iqbal S, Faiz RB, Usman M, Rehman SU.
europepmc   +1 more source

UML Diagram E-Learning Application: A Pilot Study

, 2021
Rosni Ramle, Muhammad Aqil Fahmiruddin Kamalruddin, Muhammad Isa Ismail, Muhammad Zakwan Zaina   +3 more
openalex   +1 more source

Structure–activity relationship of the allosteric effects of ivermectin at human P2X4 and GABAA receptors

British Journal of Pharmacology, Volume 182, Issue 21, Page 5286-5302, November 2025.
Abstract Background and purpose Positive allosteric modulation of the P2X4 receptor is a potential route to providing cardiovascular benefit through enhancing flow‐dependent arterial vasodilation and providing cardioprotection. However, ligands that selectively enhance P2X4 activity are absent.
Jessica L. Meades, Marcella Bassetto, Marius C. Staiculescu, Gayathri Swaminath, Samuel J. Fountain   +4 more
wiley   +1 more source

Phytochemicals and antioxidant activity of leaf extract and callus cultures of Cinnamomum camphora L. [PDF]

PLoS One
Rasool S, Rasool K, Khilji SA, Sajid ZA.
europepmc   +1 more source

Niclosamide prodrug enhances oral bioavailability and efficacy against hepatocellular carcinoma by targeting vasorin‐TGFβ signalling

British Journal of Pharmacology, Volume 182, Issue 22, Page 5517-5535, November 2025.
Abstract Background and Purpose Hepatocellular carcinoma (HCC), the third leading cause of cancer‐related deaths worldwide, has limited treatment options and high mortality rate. We previously used a bioinformatics approach to identify niclosamide (NIC) as a promising repurposed drug candidate for HCC.
Mingdian Tan, Wei Ye, Yi Liu, Xiaowu Chen, Lakshmi Huttad, Mei‐Sze Chua, Samuel So   +6 more
wiley   +1 more source

TWINVAX: conceptual model of a digital twin for immunisation services in primary health care. [PDF]

Front Public Health
De Oliveira El-Warrak L, Miceli de Farias C.   +1 more
europepmc   +1 more source

Human tissue kallikrein 14 induces the expression of IL‐6, IL‐8, and CXCL1 in skin fibroblasts through protease‐activated receptor 1 signaling

The FEBS Journal, Volume 292, Issue 21, Page 5659-5675, November 2025.
Human tissue kallikrein 14 (KLK14), a skin protease, may mediate paracrine signaling in wound healing. KLK14 released by epithelial cells activates fibroblasts via PAR‐1 activation, inducing IL‐6, IL‐8, and CXCL1 expression. These cytokines in turn promote keratinocyte proliferation and migration, resulting in wound closure.
Laura Sasiadek, Ewa Bielecka, Katherine Falkowski, Magdalena Kulczycka, Grzegorz Bereta, Anna Maksylewicz, Natalia Zubrzycka, Ewelina Dobosz, Joanna Kozieł, Justyna Drukała, Maciej Lech, Natalia Horbach, Marcin Poręba, Klaudia Brix, Grzegorz Dubin, Jan Potempa, Tomasz Kantyka   +16 more
wiley   +1 more source