Results 51 to 60 of about 87,331 (292)
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Incremental UML for Agile development: embedding UML class models in source code [PDF]
, 2017 Agile methods favor "working software over comprehensive documentation." The latter presumably includes Unified Modeling Language. UML is expensive to maintain, and it lacks good drill-down mechanisms, however, UML affords very useful visualizations ...
Braude, Eric J.
core +1 more source
UML Profile for Specifying User Interfaces of Business Applications
Symposium on Advances in Databases and Information Systems, 2011 This paper presents an approach to automatic user interface code generation that is based on an internal HCI standard that defines layout and behaviour of coarse-grained objects for enterprise business applications.
Gordana Milosavljević +3 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Lignin-Degrading Bacteria in Paper Mill Sludge
Microorganisms, 2023 The effluents generated in the paper industry, such as black liquor, have a high content of lignin and other toxic components; however, they represent a source of lignin-degrading bacteria with biotechnological potential.
Magda Rodriguez-Yupanqui +9 more
doaj +1 more source
A Practical Environment to Apply Model-Driven Web Engineering [PDF]
, 2009 The application of a model-driven paradigm in the development of Web Systems has yielded very good research results. Several research groups are defining metamodels, transformations, and tools which offer a suitable environment, known as model-driven ...
Escalona Cuaresma, María José +7 more
core +1 more source
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
ANALYSING UML-BASED SOFTWARE MODELLING LANGUAGES
Havacılık ve Uzay Teknolojileri Dergisi, 2018 UML is considered as the top popular software modelling language among practitioners. Expectedly, UML has been extended by many other languages, which tailor UML for particular domains (e.g., distributed systems, mobile systems, and embedded systems). In
Mert Ozkaya
doaj
Experiences of teaching UML within the information systems curriculum [PDF]
, 2004 The Unified Modelling Language (UML) has been a standard modelling language for the development of software intensive systems since 2000. As a consequence, the information systems (IS) curriculum, at the Cavendish School of Computer Science, University ...
Dagdeviren, H. +5 more
core
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source