Results 221 to 230 of about 51,148 (265)

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

How Salt Solvation Slows Water Dynamics While Blue-Shifting Its Dielectric Spectrum. [PDF]

J Phys Chem Lett
Pabst F, Baroni S.
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Screening of diverse Psylloidea species in Taiwan reveals the presence of both known and potentially novel "<i>Candidatus</i> Liberibacter" species in multiple psyllid lineages. [PDF]

Microbiol Spectr
Goh R-P, Liao Y-C, Yang M-M, Chu C-C.
europepmc   +1 more source

Field Responsive Swelling of Poly(Methacrylic Acid) Hydrogel-Isothermal Kinetic Analysis. [PDF]

Polymers (Basel)
Jovanovic JD, Panic VV, Begovic NN, Adnadjevic BK.   +3 more
europepmc   +1 more source

Transcending the brain disease versus disorder dichotomy: a critical realist perspective on psychiatric disorders. [PDF]

BJPsych Bull
Al Alawi M, Al Ghailani A, Al Sinawi H.
europepmc   +1 more source

Modulating the Dimensions of Rectangular Hydrazone-Based Bispyridinium Macrocyclic Receptors. [PDF]

J Org Chem
Fernández-Labandeira N, Montes de Oca I, Pazos E, Blanco-Gómez A, Peinador C, García MD.   +5 more
europepmc   +1 more source

Number-Theoretic Methods in Statistics: Theory and Applications. [PDF]

Entropy (Basel)
Fang KT, Zhou Y.
europepmc   +1 more source

Cellulose Ether/Citric Acid Systems Loaded with SrTiO₃ Nanoparticles with Solvent-Tailored Features for Energy-Related Technologies. [PDF]

Molecules
Albu RM, Avadanei MI, Curecheriu LP, Turcanu G, Stoica I, Soroceanu M, Rusu D, Varganici CD, Cojocaru V, Barzic AI.   +9 more
europepmc   +1 more source