Results 141 to 150 of about 12,911,308 (318)

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

List of referees-Quarterly Journal of Applied Theories of Economics

open access: yes
لیست داوران فصلنامه نظریه های کاربردی ...
Applied Theories of Economics, Q
core   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Department of Applied Mathematics and Statistics newsletter, February 5, 2024

open access: yes
Newsletter of the Department of Applied Mathematics and Statistics at Colorado School of ...

core  

INVEST in Change: Institutional transformation for sustainable European research cooperation - Final report for INVEST4EXCELLENCE project [PDF]

open access: yes
INVEST4EXCELLENCE (I4E) was a Horizon2020 -funded research and development project which aimed to strengthen the Research, Development and Innovation (RDI) potential of the international European University Alliance INVEST, with Karelia University of ...
Muhonen, Tiina   +2 more
core  

Feasibility of a SOFA-Derived Organ Dysfunction Score in Cats with Systemic Inflammatory Response Syndrome. [PDF]

open access: yesLife (Basel)
Codea AR   +6 more
europepmc   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

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