Results 241 to 250 of about 12,911,308 (318)

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Motor learning with force feedback instruments among laparoscopic surgeons and residents. [PDF]

J Robot Surg
G Moore A, L Servais E, Wall J, Purohit S, Garibaldi M.   +4 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Intelligent Distributed Optical Fiber Pressure Sensing for Dental Bite-Force Analysis. [PDF]

Biosensors (Basel)
Katrenova Z, Kussaiyn D, Alisherov S, Blanc W, Dostavalov A, Zollanvari A, Molardi C.   +6 more
europepmc   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Development of an Electrochemical Reactor Prototype for Biodiesel Production Powered by Photovoltaic Energy. [PDF]

ACS Omega
Rohling GF, Freire JA, Braz KMS, Oliveira Lima F, Lazarin Gallina A, Anjos T, Schumacher RF, Cabreira Soares L.   +7 more
europepmc   +1 more source

The Effect of Different Prophylactic Ankle Taping on Knee Biomechanics During Landing Tasks in Healthy Individuals: A Cross-Sectional Observational Design. [PDF]

Physiother Res Int
Koç M, Yıldırım MŞ, Canan Pakeloğlu A, Salehpour Marandi S, Bayar B, Bayar K.   +5 more
europepmc   +1 more source

An applied scholarship framework for population health impact: adapting the Boyer model for public health faculty. [PDF]

Front Public Health
Upshaw VM, Ahsan KZ, Sowah DN, Ramaswamy R, Tang W.   +4 more
europepmc   +1 more source