Applied Animal Ethics in Industrial Food Animal Production: Exploring the Role of the Veterinarian [PDF]
, 2022 Elein Hernández +2 more
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Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Motsamai Molefe. African Personhood and Applied Ethics. Makhanda: NISC (Pty) Ltd, 2020. African Books Collective. x + 138 pp. Bibliography. Index. $35.00. Paper. ISBN: 987-1920033699. [PDF]
, 2021 Hasskei M. Majeed
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Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Moral theories in teaching applied ethics. [PDF]
J Med Ethics, 2007 Lawlor R.
europepmc +1 more source
Ethics and the Use of Coercion in the Treatment of Psychiatric Patients [PDF]
, 2014 Involuntary psychiatric treatment occurs under such conditions as the medicating or placing in treatment facilities of patients without their consent. Such involuntary treatment has been litigated in the Supreme Court; however, the Court’s rulings have ...
Rushforth, Jen
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Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Practical Ethics in the Structure of Philosophical Knowledge
Интеллект. Инновации. ИнвестицииThe article is devoted to the study of practical ethics in the context of historical and philosophical tradition and modern discussions. The praxeological assessment of philosophical knowledge is considered.
Ya.V. Parusimova
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The ethics of sciences as a type of applied ethics for example one of the discoveries in modern mathematics [PDF]
, 2015 В статье исследуются проблемы этики науки как одного из видов прикладной этики. Привлекается внимание к значительному открытию в области прикладной математики.The article examines the problems of ethics of sciences as a type of applied ethics.
Phokin, N. P., Фокин, Н. П.
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