Results 131 to 140 of about 2,839,840 (302)

A sustainable management model based on business excellence as applied to mining companies

open access: yes, 2010
The success of a sustainable business project depends on different factors but there is no doubt that the excellence of business management is the single most critical factor, because of it is what connects all the others.
Botin Gonzalez, Jose Antonio   +1 more
core  

Moral Notions, with Three Papers on Plato [PDF]

open access: yes, 2004
Morality is often thought of as non-rational or sub-rational. In Moral Notions, first published in 1967, Julius Kovesi argues that the rationality of morality is built into the way we construct moral concepts.
Ewin, R. E.   +2 more
core   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Corporate ethical identity as a determinant of firm performance : a test of the mediating role of stakeholder satisfaction. [PDF]

open access: yes
In this article, we empirically assess the impact of corporate ethical identity (CEI) on a firm’s financial performance. Drawing on formulations of normative and instrumental stakeholder theory, we argue that firms with a strong ethical identity achieve ...
Berrone, Pascual   +2 more
core  

The ethics of sciences as a type of applied ethics for example one of the discoveries in modern mathematics [PDF]

open access: yes, 2015
В статье исследуются проблемы этики науки как одного из видов прикладной этики. Привлекается внимание к значительному открытию в области прикладной математики.The article examines the problems of ethics of sciences as a type of applied ethics.
Phokin, N. P., Фокин, Н. П.
core  

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

Can corporate social responsibility help us understand the credit crisis? [PDF]

open access: yes
The financial crisis which started in the United States in 2007 and which has spread throughout the world has many causes, one of which is the abundance of unethical behavior on the part of many of those who made the financial decisions, such as ...
Argandoña, Antonio
core  

A Metacognitive Approach to Trust and a Case Study: Artificial Agency [PDF]

open access: yes, 2019
Trust is defined as a belief of a human H (‘the trustor’) about the ability of an agent A (the ‘trustee’) to perform future action(s). We adopt here dispositionalism and internalism about trust: H trusts A iff A has some internal dispositions as ...
Muntean, Ioan
core   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

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