Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham +7 more
wiley +1 more source
Integrating Artificial Intelligence Into Health Informatics and Information Education: A Competency-Based Framework Using Miller's Pyramid. [PDF]
Houser SH, Flite CA, Foster SL, Morey A.
europepmc +1 more source
Medical Data and Applied Ethics: Part II: The Sources of Data [PDF]
Murphy, Edmond A.
core +1 more source
Compound Optimal Designs for Percentile Estimation in Dose-Response Models with Restricted Design Intervals [PDF]
In dose-response studies, the dose range is often restricted due to ethics concerns over drug toxicity and/or efficacy, particularly when human subjects are involved.
Biedermann, Stefanie +2 more
core
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela +13 more
wiley +1 more source
Use of Deep Learning Models in the Diagnosis of Proptosis Through Orbital Magnetic Resonance Imaging. [PDF]
Kesimal U +3 more
europepmc +1 more source
Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte +13 more
wiley +1 more source
Ethical Conflicts and Knowledge of the Code of Ethics Among Occupational Therapists in Spain. [PDF]
Emeric-Méaulle D +2 more
europepmc +1 more source
The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort
ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley +1 more source

