Results 71 to 80 of about 6,492,362 (353)

Pirin Transcriptionally Regulates PLA2G4A To Inhibit Ferroptosis in Colorectal Cancer via Lipid Profile Remodeling

open access: yesAdvanced Science, EarlyView.
This study identifies Pirin (PIR), an iron‐binding protein, as a critical ferroptosis suppressor in colorectal cancer through lipid membrane remodeling. PIR, induced by NRF2 during ferroptotic stress, transcriptionally regulates PLA2G4A to shift cellular lipid composition away from ferroptosis‐permissive polyunsaturated phospholipids.
Wei Shi   +10 more
wiley   +1 more source

Designing and validating an assessment agency questionnaire for EFL teachers: an ecological perspective

open access: yesLanguage Testing in Asia, 2023
Teacher agency is a pivotal element of professionalism and second/foreign language (L2) education. However, its role in L2 assessment has remained under-researched. Part of this negligence is due to the absence of a validated questionnaire to measure the
Farhad Ghiasvand   +2 more
doaj   +1 more source

Teaching Body Image to EFL Teenagers [PDF]

open access: yes, 2010
An extract of an Upper-Intermediate EFL coursebook for teenage learners I designed in partial requirement for MA Applied Linguistics & English Language Teaching.\ud \ud The material is centred about the topic of 'Body Image' and includes a focus on ...
Clark, Miss `Victoria L
core  

Bantu lexical reconstruction [PDF]

open access: yes, 2016
Lexical reconstruction has been an important enterprise in Bantu historical linguistics since the earliest days of the discipline. In this chapter a historical overview is provided of the principal scholarly contributions to that field of study.
Bastin, Yvonne, Bostoen, Koen
core   +2 more sources

Macrophage TRIM21 Inhibition Ameliorates Murine Acute Pancreatitis via PHB2‐Mediated Mitochondrial Stabilization

open access: yesAdvanced Science, EarlyView.
Macrophage‐derived TRIM21 drives the progression of AP via ubiquitin‐proteasome‐mediated degradation of PHB2, leading to impaired PHB2‐mediated mitophagy. Therefore, accumulation of cytosolic mtDNA hyperactivates the cGAS‐STING signaling axis, thereby amplifying inflammatory cascades.
Yansong Xu   +7 more
wiley   +1 more source

Photocatalytic Asymmetric C‐C Coupling for CO2 Reduction on Cu‐Zn Bimetallic Catalysts with Dipole‐Limiting Effects

open access: yesAdvanced Science, EarlyView.
Asymmetric Cu–Zn dual sites on EDTA‐grafted Ti‐MOF amplify the dipole‐limiting domain field (DLDF), facilitating C–C coupling. This strategy yields an exceptional C2H4 production rate of 308.72 µmol g−1 h−1 with 98.4% electron selectivity in photocatalytic CO2 reduction, highlighting the potential of asymmetric site engineering and local field ...
Peidong Ma   +8 more
wiley   +1 more source

Less Common Languages, Common Needs for K-12 Instructors [PDF]

open access: yesJournal of the National Council of Less Commonly Taught Languages, 2022
This study sought to understand the needs of U.S. K-12 teachers as they guide students learning languages with non-Roman writing systems, which we have termed “Languages with Diverse Written Representations (LDWR).” While there is a growing body of ...
Leslie Fink   +2 more
doaj  

Language testing and assessment in applied linguistics: Identifying reciprocity in applied linguistic research [PDF]

open access: yes, 2008
The rationale for the seminar was primarily that there are links between language testing and assessment on one hand and applied linguistics on the other which could be mutually beneficial, but are not necessarily perceived as such.
Rea-Dickins, Pauline   +2 more
core  

Compensatory Interplay Between Clarin‐1 and Clarin‐2 Deafness‐Associated Proteins Governs Phenotypic Variability in Hearing

open access: yesAdvanced Science, EarlyView.
Functional compensation between clarin‐1 and clarin‐2 in cochlear hair cells. Hearing loss associated with CLRN1 mutations shows striking phenotypic variability; however, the underlying mechanisms remain poorly understood. This study reveals that clarin‐1 and clarin‐2 function cooperatively in cochlear hair cells to sustain mechanoelectrical ...
Maureen Wentling   +17 more
wiley   +1 more source

Preliminary Pages

open access: yesColombian Applied Linguistics Journal, 2018
Preliminary Pages- Volume 20 No ...
Colombian Applied Linguistics Journal
doaj   +2 more sources

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