Results 41 to 50 of about 396,120 (300)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Riga – Plate flow of γ Al2O3-water/ethylene glycol with effective Prandtl number impacts

open access: yesHeliyon, 2019
In many industrial processes, the cooling process can be improved by varying the flow geometry or changing the additives in the working fluid. The present work concentrates on the flow of γ Al2O3 –Water/Ethylene Glycol over a Gailitis and Lielausis ...
N. Vishnu Ganesh   +3 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Intelligent Mathematics Ii: Applied Mathematics and Approximation Theory [PDF]

open access: yes, 2016
This special volume is a collection of outstanding more applied articles presented in AMAT 2015 held in Ankara, May 28-31, 2015, at TOBB Economics and Technology University.

core   +1 more source

Uranyl nitrate crystallizer performance with changing solution level

open access: yesHeliyon, 2019
This manuscript described a dynamic simulation of uranyl nitrate crystallization in a linear crystallizer. Furthermore, a mathematical model of the crystallizer supply system was developed with a related control algorithm; the model contained two piston ...
Igor S. Nadezhdin   +4 more
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Maximal quasi-bicliques with balanced noise tolerance: Concepts and co-clustering applications [PDF]

open access: yes, 2008
Society for Industrial and Applied Mathematics - 8th SIAM International Conference on Data Mining 2008, Proceedings in Applied Mathematics 130172 ...
Wong, L   +11 more
core   +1 more source

Investigation of generalized piezoelectric-thermoelastic problem with nonlocal effect and temperature-dependent properties

open access: yesHeliyon, 2018
In the generalized thermoelasticity with fractional order heat conduction and nonlocal elasticity, a generalized piezoelectric-thermoelastic problem of a both-end-fixed finite length piezoelectric rod with temperature-dependent properties and subjected ...
Danni Li, Tianhu He
doaj   +1 more source

On the Role of Applied Mathematics

open access: yesAdvances in Mathematics, 1976
AbstractThis paper concerns itself with the nature of applied mathematics, and how to make its role effective. Its differences from pure mathematics and from theoretical sciences are pointed out with the help of illustrative examples. Recommendations are made for supporting a program of education and research in applied mathematics to make it an ...
openaire   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

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