Advanced Science, EarlyView.Single‐molecule fluorescence microscopy is combined with proteomic profiling to fingerprint the morphology and composition of TDP‐43 protein aggregates found in post‐mortem motor neuron disease brain tissues. Aggregate fingerprints can distinguish disease from control donors and detect unexpected TDP‐43 pathology in SOD1‐MND.
Dezerae Cox +9 more
wiley +1 more source
Applied Psychology: Health and Well‐Being Editorial [PDF]
, 2008 Ralf Schwarzer, Christopher Peterson
openalex +1 more source
Advanced Science, EarlyView.This study uses a high‐resolution DNA methylation reference panel for 19 immune cell‐types, as well as transcriptomic, metabolomic, and large population cohort data to show that age‐related epigenetic heterogeneity within monocytes correlates with inflammaging, biological age, and all‐causemortality, and does so more strongly than existing monocyte ...
Xiaolong Guo +17 more
wiley +1 more source
Dynamic Neural Deactivation Bridges Direct and Competitive Inhibition Processes
Advanced Science, EarlyView.Dynamic neural deactivation bridges traditionally distinct inhibitory mechanisms—direct inhibition and competition‐induced inhibition—revealing a common neural signature across modalities. Multimodal neuroimaging and behavioral experiments demonstrate a temporal dynamic characterized by progressive frontoparietal activation decay and enhanced sensory ...
Zhenhong He +6 more
wiley +1 more source
Reviews: Research Methods and Statistics in Psychology (4th Edition), Connect College to Career: A Student's Guide to Work and Life Transitions, The Smart Study Guide: Psychological Techniques for Student Success, Adulthood, Applied Statistics with SPSS, Biological Psychology (2nd Edition), Essential Social Psychology, Introduction to Infant Development (2nd Edition), Introduction to Consciousness, Psychological Testing: An Introduction (2nd Edition), Dynamic Assessment in Practice: Clinical … [PDF]
, 2008 David Booth +10 more
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Big Data and AI‐Powered Modeling: A Pathway to Sustainable Precision Animal Nutrition
Advanced Science, EarlyView.This review summarizes the current landscape of big data and AI‐powered modeling in animal nutrition, covering techniques including intelligent data acquisition, data augmentation, explainable machine learning, heuristic algorithms, and life cycle assessment‐based sustainability evaluation.
Shuai Zhang +3 more
wiley +1 more source
Integration of Genetic and Imaging Data for Alzheimer's Disease Diagnosis and Interpretation
Advanced Science, EarlyView.AlzCLIP is a novel contrastive learning framework that integrates single nucleotide polymorphism (SNP) profiles and MRI‐derived imaging features into a unified representation space to improve Alzheimer's disease (AD) diagnosis and interpretation. By achieving superior diagnostic accuracy and revealing key genetic and structural contributors to AD risk,
Yanfei Wang +7 more
wiley +1 more source
The Value of Reflective Practice in Professional Development: An Applied Sport Psychology Review [PDF]
, 2010 Brendan Cropley +3 more
openalex +1 more source