Results 131 to 140 of about 18,900,974 (296)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Frankfurt University News 3/16 [PDF]

, 2019
Aktuelle Kurzinformationen der Frankfurt University of Applied ...
Der Präsident der Frankfurt University of Applied Sciences
core  

Soft wearable thermo+touch haptic interface for virtual reality

iScience
Summary: Touch is an inherent source of tactile sensation in everyday life, followed by vision and audition. For rich tactile feedback, multimodal haptic feedback is necessary because a single touch simultaneously excites multiple types of tactile ...
Seohu Lee, Seongkwan Jang, Youngsu Cha
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

A human-system integration framework and its application for special vehicle interface design under typical human readiness levels

iScience
Summary: Life cycle Human System Integration (HSI) practices are crucial for optimizing human system performance, reducing costs, and ensuring safety. To address the limited HSI practices under typical Human Readiness Levels (HRLs), our study proposes an
Chuanyan Feng, Shuang Liu, Xiaoru Wanyan, Zhenjia Sun, Fang Xie   +4 more
doaj   +1 more source

[Influence of distance learning on students' physical activity and nutrition]. [PDF]

Pravent Gesundh, 2023
Rathgeber T, Zenzmaier C, Nöhammer E.
europepmc   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Applied Sciences

Applied Sciences (ISSN 2076-3417) provides an advanced forum on all aspects of applied natural sciences. It publishes reviews, research papers and communications.
Santangelo Angela
core  

Almanach 2016 : Ankommen [PDF]

, 2019
Jahrbuch der Frankfurt University of Applied ...
Der Präsident der Frankfurt University of Applied Sciences
core  

Polarization-insensitive narrowband reflective wavefront manipulation through all-dielectric anisotropic subwavelength structures

iScience
Summary: Local metasurfaces provide high flexibility in shaping wavefronts but suffer from poor frequency selectivity. Here, we numerically present a reflective all-dielectric metasurface platform achieving simultaneous local phase control and spectral ...
Meiyan Pan, Yanxin Lu, Jintao Wang, Yihang Chen   +3 more
doaj   +1 more source