Results 41 to 50 of about 2,669,677 (322)
Applied Sciences and the Environment [PDF]
Electronic Green Journal, 1999 Review: Applied Sciences and the Environment Editors: D. Almorza and H.M. Ramos Reviewed by Xavier E. Gros European Commission, Joint Research Center, Holland Almorza, D. and H.M. Ramos, eds. Applied Sciences and the Environment. Boston, Southampton: WIT Press, 1998. 360 p. US$184.00 hardbound ISBN: 1-85312-603-9. The fourth volume in the Environmental
openaire +3 more sources
Materials Informatics: An Algorithmic Design Rule [PDF]
arXiv, 2023 Materials informatics, data-enabled investigation, is a "fourth paradigm" in materials science research after the conventional empirical approach, theoretical science, and computational research. Materials informatics has two essential ingredients: fingerprinting materials proprieties and the theory of statistical inference and learning.
arxiv
The dual nature of TDC – bridging dendritic and T cells in immunity
FEBS Letters, EarlyView.TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley +1 more source
FEBS Letters, EarlyView.In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali +3 more
wiley +1 more source
What Does Information Science Offer for Data Science Research?: A Review of Data and Information Ethics Literature [PDF]
Journal of Data and Information Science (2022)This paper reviews literature pertaining to the development of data science as a discipline, current issues with data bias and ethics, and the role that the discipline of information science may play in addressing these concerns. Information science research and researchers have much to offer for data science, owing to their background as ...
arxiv +1 more source
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
How do scientific disciplines evolve in applied sciences? The properties of scientific fission and ambidextrous scientific drivers [PDF]
arXiv, 2019 One of the fundamental questions in science is how scientific disciplines evolve and sustain progress in society. No studies to date allows us to explain the endogenous processes that support the evolution of scientific disciplines and emergence of new scientific fields in applied sciences of physics.
arxiv
FEBS Letters, EarlyView.Toll‐like receptors (TLRs) are important in the innate immune system. This study explores the zinc‐binding ability of the TLR2 TIR domain (TLR2TIR). We found that TLR2TIR binds zinc with nanomolar affinity through its cysteine residues. Two of them, C673 and C713, are vital for receptor activation, indicating that zinc may play a role in initiating ...
Vladislav A. Lushpa +8 more
wiley +1 more source