Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Young women's perspectives on unwanted sexual attention: navigating boundaries, responsibility, and prevention - a qualitative study. [PDF]
Salemonsen E, Giertsen ACW, Seth M.
europepmc +1 more source
Report and publications list: Centre for Applied Social Sciences December 1983 [PDF]
Centre for Applied Social Sciences
core
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
An assessment of sensory sensitivity, including certain anhedonia dimensions, in patients with schizophrenia using transcutaneous electrical nerve stimulation. [PDF]
Witkoś J +2 more
europepmc +1 more source
Twenty-third annual report for the period 1st January 1976 to 31st December 1977 [PDF]
Centre for Applied Social Sciences
core
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Design and validation of a qualitative interview for the study of the role of physical activity in urban public spaces in the social inclusion of immigrant women (Spanish version). [PDF]
Blanco-Ayala A +3 more
europepmc +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Effectiveness of a five-component multimodal intervention on executive function in children with Autism spectrum disorder: A study protocol for a randomized controlled trial. [PDF]
Hossain KMA +6 more
europepmc +1 more source

