Results 71 to 80 of about 2,856,816 (301)

Explorations in Applied Social Science

Social Problems, 1956
Not so long ago the words "social engineer" were a term of opprobrium. They carried with them the suspicion that such a social scientist had somehow betrayed his vow of dispassionate objectivity and had sold his scientific heritage for a tasteless mess of popularity.
openaire   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Applied social sciences: concepts and perspectives

, 2022
The book “Applied social sciences: concepts and perspectives vol.01, edited and published by South Florida Publishing, gathers ten chapters that approach themes of relevance in the context of education and are available in Spanish. The book will feature, a study on establishing the development of literary transcendentalism and how it manifests itself ...
openaire   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Experiences of members of the care triad on transitioning from home to a nursing home: a qualitative study

BMC Geriatrics
Background The transition from home to a nursing home is an emotionally and organisationally challenging process for the care triad, consisting of older adults in need of care, their informal caregivers, and health professionals. Although this transition
Stefanie Skudlik , Katharina Lüftl, Regina Thalhammer, Melina Zaglacher, Martin Müller   +4 more
doaj   +1 more source

Informal caregivers’ judgements on sharing care with home care professionals from an intersectional perspective: the influence of personal and situational characteristics

International Journal of Integrated Care, 2019
Introduction: The European policy emphasis on providing informal care at home will increase contact between caregivers and home care professionals, which makes it more important for them to find satisfying ways to share care.
Yvette Wittenberg, Alice de Boer, Inger Plaisier, Arnoud Verhoeff, Rick Kwekkeboom   +4 more
doaj   +1 more source

Living in the Era of an Ideological Climate of Globalisation: A Study of Psychological Sense of Community Among Young and Older Adults in Two Cultures (India and Norway). Challenges for Community Psychology and the Applied Social Sciences. [PDF]

Front Psychol, 2021
Bahl NKH, Nafstad HE, Blakar RM, Langvik E.   +3 more
europepmc   +1 more source

Developing learner autonomy and critical thinking in masters' students [PDF]

, 2006
This paper analyses the idea of student autonomy, which was discussed within the specific context of the MSc in Social Research Methods offered by the London Metropolitan University’s Department of Applied Social Sciences (DASS) - more specifically ...
Hardy, Nick
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source