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Department of Applied Mathematics and Statistics Newsletter, September 15, 2025

Newsletter of the Department of Applied Mathematics and Statistics at Colorado School of ...

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Department of Applied Mathematics and Statistics newsletter, February 12, 2024 [PDF]

Newsletter of the Department of Applied Mathematics and Statistics at Colorado School of ...

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Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Applied Statistics [PDF]

Journal of the Royal Statistical Society Series C: Applied Statistics, 2017
R. J. Boys, N. Stallard, Q. Chen, P. Clarke, R. Deardon, C. Gaetan, S. Greven, D. Husmeier, K. Kalogeropoulos, A. Lewin, S. Liverani, J. Mateu, R. McCrea, D. Oberski, T. Ogden, P. Ranjan, J. Roy, T. Scheike, J. Schildcrout, S. Shortreed, N. A. Wages   +20 more
openaire   +2 more sources

Department of Applied Mathematics and Statistics Newsletter, February 16, 2026

Newsletter of the Department of Applied Mathematics and Statistics at Colorado School of ...

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Department of Applied Mathematics and Statistics Newsletter, October 6, 2025 [PDF]

Newsletter of the Department of Applied Mathematics and Statistics at Colorado School of ...

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2015-2016 AAAL Statistics

, 2017
Annual institutional statistics collection for AAAL member ...
Statistics, AAAL
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Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Department of Applied Mathematics and Statistics Newsletter, November 3, 2025

Newsletter of the Department of Applied Mathematics and Statistics at Colorado School of ...

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Department of Applied Mathematics and Statistics Newsletter, January 12, 2026 [PDF]

Newsletter of the Department of Applied Mathematics and Statistics at Colorado School of ...

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