Results 111 to 120 of about 142,782 (274)

The syntactic processing of particles in Japanese spoken language [PDF]

open access: yes, 1999
Particles fullfill several distinct central roles in the Japanese language. They can mark arguments as well as adjuncts, can be functional or have semantic funtions. There is, however, no straightforward matching from particles to functions, as, e.g., GA
Siegel, Melanie
core   +5 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Smart Scheduling (SMASCH): multi-appointment scheduling system for longitudinal clinical research studies. [PDF]

open access: yesJAMIA Open, 2022
Vega C   +9 more
europepmc   +1 more source

Quantum Algorithm for Appointment Scheduling

open access: yesJournal of Quantum Computing, 2019
Suppose a practical scene that when two or more parties want to schedule an appointment, they need to share their calendars with each other in order to make it possible. According to the present result the whole communication cost to solve this problem should be their calendars’ length by using a classical algorithm.
Wenbin Yu   +4 more
openaire   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Mothers’ Perceived Barriers to and Recommendations for Health Care Appointment Keeping for Children Who Have Cerebral Palsy

open access: yesGlobal Qualitative Nursing Research, 2019
Children with cerebral palsy (CP) require ongoing rehabilitation services to address complex health care needs. Attendance at appointments ensures continuity of care and improves health and well-being.
Marilyn Ballantyne   +5 more
doaj   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Identifying Complex Scheduling Patterns Among Patients With Cancer With Transportation and Housing Needs: Feasibility Pilot Study

open access: yesJMIR Cancer
BackgroundPatients with cancer frequently encounter complex treatment pathways, often characterized by challenges with coordinating and scheduling appointments at various specialty services and locations.
Allan Fong   +5 more
doaj   +1 more source

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