Results 111 to 120 of about 26,383 (257)

Patient-Centered Appointment Scheduling: a Call for Autonomy, Continuity, and Creativity. [PDF]

J Gen Intern Med, 2021
Matulis JC, McCoy R.
europepmc   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Investigating Disparities in Physical Therapy Utilization: An Intersectionality Perspective

Archives of Rehabilitation Research and Clinical Translation
Objective: To investigate the role of race, ethnicity, language, insurance payor, and socioeconomic status, both individually and through an intersectional framework, on outpatient physical therapy (PT) utilization.
Lauren Rimmel, PT, DPT, Kathleen Taglieri-Noble, PT, DPT, Rebecca Pham, PT, DPT, Joseph Tolland, PT, DPT, Saloni Doshi, PT, DPT, Nicholas Capobianco, PT, DPT, Anshul Kumar, PhD   +6 more
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

An Electronic Health Record–Based Automated Self-Rescheduling Tool to Improve Patient Access: Retrospective Cohort Study

Journal of Medical Internet Research
BackgroundIn many large health centers, patients face long appointment wait times and difficulties accessing care. Last-minute cancellations and patient no-shows leave unfilled slots in a clinician’s schedule, exacerbating delays ...
Smitha Ganeshan, Andrew W Liu, Anne Kroeger, Prerna Anand, Richard Seefeldt, Alexis Regner, Diana Vaughn, Anobel Y Odisho, Michelle Mourad   +8 more
doaj   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Lessons learned from a sustained mobile prenatal care delivery program: results from a mixed-methods evaluation to understand appointment attendance and patient satisfaction

BMC Pregnancy and Childbirth
Background Persistent racial and socioeconomic disparities in prenatal care attendance in the United States are driven by structural barriers, including transportation challenges, inflexible scheduling, and limited access to culturally responsive ...
Stacey Cunnington, Candice Mims, Rebecca Barbeau, Sonia Booker, Mary Ann Abiado, Gain Robinson, Salina Tesfay, Cintia Ulloa-Hays, Donna Beach, Nimo Farah, Eleanor Porter, Rebecca Rudel, Jacey A. Greece   +12 more
doaj   +1 more source

Using Simulation Optimization to Solve Patient Appointment Scheduling and Examination Room Assignment Problems for Patients Undergoing Ultrasound Examination. [PDF]

Healthcare (Basel), 2022
Chen PS, Chen GY, Liu LW, Zheng CP, Huang WT.   +4 more
europepmc   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source